User profiles for Harald H. Sitte

Harald H. Sitte

Professor of Psychopharmacology, Medical University Vienna
Verified email at meduniwien.ac.at
Cited by 10728

[HTML][HTML] Powerful cocaine-like actions of 3, 4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products

…, SR Goldberg, CR Lupica, HH Sitte… - …, 2013 - nature.com
The abuse of psychoactive ‘bath salts’ containing cathinones such as 3, 4-methylenedioxypyrovalerone
(MDPV) is a growing public health concern, yet little is known about their …

[HTML][HTML] Amphetamines, new psychoactive drugs and the monoamine transporter cycle

HH Sitte, M Freissmuth - Trends in pharmacological sciences, 2015 - cell.com
In monoaminergic neurons, the vesicular transporters and the plasma membrane transporters
operate in a relay. Amphetamine and its congeners target this relay to elicit their actions: …

[PDF][PDF] Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport

…, DG McMahon, RJ Colbran, LC Daws, HH Sitte… - Neuron, 2006 - cell.com
Efflux of dopamine through the dopamine transporter (DAT) is critical for the psychostimulatory
properties of amphetamines, but the underlying mechanism is unclear. Here we show that …

[HTML][HTML] Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation

…, R Mittermayr, H Redl, WG Junger, HH Sitte… - Journal of Biological …, 2014 - ASBMB
Shock wave treatment accelerates impaired wound healing in diverse clinical situations.
However, the mechanisms underlying the beneficial effects of shock waves have not yet been …

[HTML][HTML] Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in …

…, O Kudlacek, M Freissmuth, EA Singer, HH Sitte - Journal of Biological …, 2001 - ASBMB
Recent biochemical studies indicate that the serotonin transporter can form oligomers. We
investigated whether the human serotonin transporter (hSERT) can be visualized as an …

Actovegin®: a biological drug for more than 5 decades.

…, MW Elmlinger, G Lauer, G Nell, HH Sitte - Wiener Medizinische …, 2011 - europepmc.org
Actovegin (®) is a biological drug manufactured from a natural source: it is a calf blood
hemodialysate. Its therapeutic benefits stem from a variety of pharmacodynamic actions that can …

[HTML][HTML] Missense dopamine transporter mutations associate with adult parkinsonism and ADHD

…, HH Sitte, C Loland, L Shi, H Weinstein… - The Journal of …, 2014 - Am Soc Clin Investig
Parkinsonism and attention deficit hyperactivity disorder (ADHD) are widespread brain
disorders that involve disturbances of dopaminergic signaling. The sodium-coupled dopamine …

Anomalous dopamine release associated with a human dopamine transporter coding variant

…, M Schmudermaier, M Freissmuth, HH Sitte… - Journal of …, 2008 - Soc Neuroscience
Dopamine (DA) signaling at synapses is tightly coordinated through opposing mechanisms
of vesicular fusion-mediated DA release and transporter-mediated DA clearance. Altered …

Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3

…, WC Hong, MM Dorostkar, R Janz, HH Sitte… - Journal of …, 2009 - Soc Neuroscience
Uptake through the dopamine transporter (DAT) represents the primary mechanism used to
terminate dopaminergic transmission in brain. Although it is well known that dopamine (DA) …

[HTML][HTML] The N terminus of monoamine transporters is a lever required for the action of amphetamines

…, AH Newman, GF Ecker, M Freissmuth, HH Sitte - Journal of Biological …, 2010 - ASBMB
The serotonin transporter (SERT) terminates neurotransmission by removing serotonin from
the synaptic cleft. In addition, it is the site of action of antidepressants (which block the …