Na v 2/NaG is a putative sodium channel, whose physiological role has long been an
enigma. We generatedNa v 2 gene-deficient mice by inserting the lacZ gene. Analysis of the …

Male and female rats were given a single oral dose of [phenoxyphenyl-14C] pyriproxyfeTt [4-phenoxyphenyl
(R, S)-2-(2-pyridyloxy) propyl ether] at 2 (low dose) or 1000 (high dose) mg/…

To examine the metabolic fate of 7-fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4-(2-propynyl)-2H-1,4-benzoxazin-3(4H)-one
(S-53482), rats were given a single oral dose of [phenyl- 14 C]-…

The urinary and fecal metabolites of orally administered 2-tert-butyl-4-hydroxyanisole (2-BHA)
and 3-tert-butyl-4-hydroxyanisole (3-BHA) in rats were identified. Samples of 2-day …

Male and female Sprague-Dawley rats, 7 weeks old, were given a single oral dose of [phenyl-
14 C]-S-23031 [pentyl 2-chloro-4-fluoro-5-(3,4,5,6-tetrahydrophthalimido)phenoxyacetate] …

Male rats were orally given pentyl 2-chloro-4-fluoro-5-(3,4,5,6-tetrahydrophthalimido)phenoxyacetate
(flumiclorac pentyl, S-23031) labeled with 14 C at 250 (mg/kg)/day for 6 …

Male and female Sprague-Dawley rats received repeated oral administration of 14 C-2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl
3- [5-(trifluoromethyl)-2-pyridyloxy]propyl ether ( 14 C-…

The metabolism of flufenpyr-ethyl [ethyl 2-chloro-5-[1,6-dihydro-5-methyl-6-oxo-4-(trifluoromethyl)pyridazin-1-yl]-4-fluorophenoxyacetate]
was examined in rats and mice. [Phenyl- 14 C]…

MATERIALS AND METHODS 1. Designation of Compounds The abbreviations used in this
report are summarized in Table 1. 2. Chemicals Procymidone and its metabolites were …

Investigating human exposure to dioxins is an urgent task that needs to be undertaken by the
Japanese government, because deleterious effects of dioxins on human health have been …