User profiles for Haydyn D. T. Mertens

Haydyn David Thomas Mertens

Former Senior Technical Officer, EMBL; Currently Medical Student (University of …
Verified email at embl-hamburg.de
Cited by 8494

Structural characterization of proteins and complexes using small-angle X-ray solution scattering

HDT Mertens, DI Svergun - Journal of structural biology, 2010 - Elsevier
Small-angle scattering of X-rays (SAXS) is an established method for the low-resolution
structural characterization of biological macromolecules in solution. The technique provides …

[HTML][HTML] New developments in the ATSAS program package for small-angle scattering data analysis

…, M Gajda, C Gorba, HDT Mertens… - Journal of applied …, 2012 - scripts.iucr.org
New developments in the program package ATSAS (version 2.4) for the processing and
analysis of isotropic small-angle X-ray and neutron scattering data are described. They include (i…

[HTML][HTML] Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering

G Tria, HDT Mertens, M Kachala, DI Svergun - IUCrJ, 2015 - scripts.iucr.org
Dynamic ensembles of macromolecules mediate essential processes in biology. Understanding
the mechanisms driving the function and molecular interactions of `unstructured' and …

[HTML][HTML] ATSAS 3.0: expanded functionality and new tools for small-angle scattering data analysis

…, A Panjkovich, HDT Mertens… - Journal of applied …, 2021 - scripts.iucr.org
The ATSAS software suite encompasses a number of programs for the processing,
visualization, analysis and modelling of small-angle scattering data, with a focus on the data …

A low-background-intensity focusing small-angle X-ray scattering undulator beamline

…, AM Hawley, DJ Cookson, HDT Mertens… - Journal of Applied …, 2013 - scripts.iucr.org
The SAXS/WAXS beamline at the Australian Synchrotron is an advanced and flexible undulator
X-ray scattering beamline used for small- and wide-angle X-ray scattering analysis on a …

[HTML][HTML] Combining NMR and small angle X-ray scattering for the study of biomolecular structure and dynamics

HDT Mertens, DI Svergun - Archives of biochemistry and biophysics, 2017 - Elsevier
Small-angle X-ray scattering (SAXS) and Nuclear Magnetic Resonance (NMR) are established
methods to analyze the structure and structural transitions of biological macromolecules …

Structural basis for engagement by complement factor H of C3b on a self surface

…, AP Herbert, D Kavanagh, HDT Mertens… - Nature structural & …, 2011 - nature.com
Complement factor H (FH) attenuates C3b molecules tethered by their thioester domains to
self surfaces and thereby protects host tissues. Factor H is a cofactor for initial C3b …

Structure, topology and function of the translocase of the outer membrane of mitochondria

AJ Perry, KA Rimmer, HDT Mertens, RF Waller… - Plant Physiology and …, 2008 - Elsevier
Proteins destined for the mitochondria required the evolution of specific and efficient
molecular machinery for protein import. The subunits of the import translocases of the inner …

[HTML][HTML] The crystal structure of netrin-1 in complex with DCC reveals the bifunctionality of netrin-1 as a guidance cue

…, J Zhang, M Chegkazi, Y Wu, G Schenk, HDT Mertens… - Neuron, 2014 - cell.com
Netrin-1 is a guidance cue that can trigger either attraction or repulsion effects on migrating
axons of neurons, depending on the repertoire of receptors available on the growth cone. …

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis

…, L Ciccarelli, CM Bunduc, HDT Mertens… - Nature …, 2017 - nature.com
Mycobacteria are characterized by their impermeable outer membrane, which is rich in mycolic
acids 1. To transport substrates across this complex cell envelope, mycobacteria rely on …