Balanced development of excitatory and inhibitory synapses is required for normal brain
function, and an imbalance in this development may underlie the pathogenesis of many …

What causes critical periods (CPs) to open? For the best-studied case, ocular dominance
plasticity in primary visual cortex in response to monocular deprivation (MD), the maturation of …

STXBP1 and SCN2A gene mutations are observed in patients with epilepsies, although the
circuit basis remains elusive. Here, we show that mice with haplodeficiency for these genes …

Severe plastic deformation (SPD) is effective in producing bulk ultrafine-grained and
nanostructured materials with large densities of lattice defects. This field, also known as NanoSPD, …

Loss-of-function mutations in human SCN1A gene encoding Na v 1.1 are associated with a
severe epileptic disorder known as severe myoclonic epilepsy in infancy. Here, we …

A neural network model for generation of motor command was proposed in our earlier paper.
This model contains a feedback loop (transcortical loop), an internal neural model of motor …

How individual receptive field properties are formed in the maturing sensory neocortex remains
largely unknown. The shortening of N-methyl-d-aspartate (NMDA) receptor currents by …

A general theory of movement-pattern perception based on bi-directional theory for sensory-motor
integration can be used for motion capture and learning by watching in robotics. We …

Dravet syndrome is a severe epileptic encephalopathy mainly caused by heterozygous
mutations in the SCN1A gene encoding a voltage-gated sodium channel Nav1.1. We previously …

Corrosion of ultra-fine grain (UFG) copper fabricated by equal-channel angular pressing (ECAP)
has been investigated in comparison with that in recrystallized coarse grain (CG) copper…