User profiles for Huimei Yu

Huimei Yu

Johns Hopkins University
Verified email at jhu.edu
Cited by 1383

A library of atomically thin metal chalcogenides

…, X Huang, Y Zhou, Y Chen, J Xia, H Wang, Y Xie, H Yu… - Nature, 2018 - nature.com
Investigations of two-dimensional transition-metal chalcogenides (TMCs) have recently
revealed interesting physical phenomena, including the quantum spin Hall effect 1 , 2 , valley …

Synaptic dysregulation in a human iPS cell model of mental disorders

…, KJ Yoon, J Shin, C Zhang, G Makri, D Nauen, H Yu… - Nature, 2014 - nature.com
Dysregulated neurodevelopment with altered structural and functional connectivity is believed
to underlie many neuropsychiatric disorders 1 , and ‘a disease of synapses’ is the major …

Composition and phase engineering of metal chalcogenides and phosphorous chalcogenides

…, Z Wang, YC Lin, J Shi, R Zhang, Y Zheng, H Yu… - Nature Materials, 2023 - nature.com
Two-dimensional (2D) materials with multiphase, multielement crystals such as transition
metal chalcogenides (TMCs) (based on V, Cr, Mn, Fe, Cd, Pt and Pd) and transition metal …

[HTML][HTML] Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells

TA Juopperi, WR Kim, CH Chiang, H Yu, RL Margolis… - Molecular brain, 2012 - Springer
Background Huntington’s Disease (HD) is a devastating neurodegenerative disorder that
clinically manifests as motor dysfunction, cognitive impairment and psychiatric symptoms. …

Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair

H Yu, Y Su, J Shin, C Zhong, JU Guo, YL Weng… - Nature …, 2015 - nature.com
Contrary to the long-held belief that DNA methylation of terminally differentiated cells is
permanent and essentially immutable, post-mitotic neurons exhibit extensive DNA demethylation…

Biosynthesis of silver nanoparticles by the endophytic fungus Epicoccum nigrum and their activity against pathogenic fungi

Y Qian, H Yu, D He, H Yang, W Wang, X Wan… - Bioprocess and …, 2013 - Springer
There is an enormous interest in developing safe, cost-effective and environmentally friendly
technologies for nano-materials synthesis. In the present study, extracellular biosynthesis of …

Inhibition of autophagy enhances cisplatin cytotoxicity through endoplasmic reticulum stress in human cervical cancer cells

Y Xu, H Yu, H Qin, JS Kang, C Yu, J Zhong, J Su, HY Li… - Cancer letters, 2012 - Elsevier
The function of autophagy in cisplatin-treated cancer cells is not fully understood. Cisplatin
treatment induced degradation of ubiquitinated proteins by autophagy, which reduced …

Electronegativity‐Induced Charge Balancing to Boost Stability and Activity of Amorphous Electrocatalysts

Y Zhou, W Hao, X Zhao, J Zhou, H Yu, B Lin… - Advanced …, 2022 - Wiley Online Library
Amorphization is an efficient strategy to activate intrinsically inert catalysts. However, the low
crystallinity of amorphous catalysts often causes high solubility and poor electrochemical …

p62/SQSTM1 involved in cisplatin resistance in human ovarian cancer cells by clearing ubiquitinated proteins

H Yu, J Su, Y Xu, J Kang, H Li, L Zhang, H Yi… - European journal of …, 2011 - Elsevier
Mechanisms of cisplatin resistance in cancer cells are not fully understood. Here, we show
a critical role for the ubiquitin-binding protein p62/SQSTM1 in cisplatin resistance in human …

The role of epigenetic mechanisms in the regulation of gene expression in the nervous system

…, M von Schimmelmann, A Schaefer, H Yu… - Journal of …, 2016 - Soc Neuroscience
Neuroepigenetics is a newly emerging field in neurobiology that addresses the epigenetic
mechanism of gene expression regulation in various postmitotic neurons, both over time and …