User profiles for Hyun Kyoung Lee

Hyun Kyoung Lee

Associate Professor, Baylor College of Medicine
Verified email at bcm.edu
Cited by 2557

Identification of diverse astrocyte populations and their malignant analogs

CC John Lin, K Yu, A Hatcher, TW Huang, HK Lee… - Nature …, 2017 - nature.com
Astrocytes are the most abundant cell type in the brain, where they perform a wide array of
functions, yet the nature of their cellular heterogeneity and how it oversees these diverse …

[PDF][PDF] Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis

P Kang, HK Lee, SM Glasgow, M Finley, T Donti… - Neuron, 2012 - cell.com
Transcriptional cascades that operate over the course of lineage development are fundamental
mechanisms that control cellular differentiation. In the developing central nervous system …

Ethylene suppression of sugar-induced anthocyanin pigmentation in Arabidopsis

…, PK Das, SC Jeoung, JY Song, HK Lee… - Plant …, 2010 - academic.oup.com
Anthocyanin accumulation is regulated negatively by ethylene signaling and positively by
sugar and light signaling. However, the antagonistic interactions underlying these signalings …

TLR3‐mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3‐induced IP‐10 …

C Park, S Lee, IH Cho, HK Lee, D Kim, SY Choi, SB Oh… - Glia, 2006 - Wiley Online Library
Viral infection is one of the leading causes of brain encephalitis and meningitis. Recently, it
was reported that Toll‐like receptor‐3 (TLR3) induces a double‐stranded RNA (dsRNA)‐…

[HTML][HTML] Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronaviruses 229E and OC43

HK Lee, BH Lee, SH Seok, MW Baek… - Journal of veterinary …, 2010 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome (SARS) is a life-threatening disease for which accurate
diagnosis is essential. Although many tools have been developed for the diagnosis of SARS, …

Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration

J Jung, W Cai, HK Lee, M Pellegatta… - Journal of …, 2011 - Soc Neuroscience
The mechanisms that trigger Wallerian degeneration (WD) of peripheral nerves after injury
are not well understood. During the early period of WD, fragmentation of myelin into ovoid …

[HTML][HTML] NIST interlaboratory study on glycosylation analysis of monoclonal antibodies: comparison of results from diverse analytical methods

…, S Klapoetke, R Cao, JY Kim, HK Lee, JY Lee… - Molecular & Cellular …, 2020 - ASBMB
Glycosylation is a topic of intense current interest in the development of biopharmaceuticals
because it is related to drug safety and efficacy. This work describes results of an …

[HTML][HTML] Integrated GlycoProteome Analyzer (I-GPA) for automated identification and quantitation of site-specific N-glycosylation

GW Park, JY Kim, H Hwang, JY Lee, YH Ahn, HK Lee… - Scientific reports, 2016 - nature.com
Human glycoproteins exhibit enormous heterogeneity at each N-glycosite, but few studies
have attempted to globally characterize the site-specific structural features. We have …

Development of myelinating glia: An overview

CD Cristobal, HK Lee - Glia, 2022 - Wiley Online Library
… -34551 to Hyun Kyoung Lee), NIH/NINDS (R01NS110859 to Hyun Kyoung Lee), and the
Mark A. Wallace Endowment established by an anonymous donor (to Hyun Kyoung Lee). Parts …

Self-assembling multidomain peptide hydrogels accelerate peripheral nerve regeneration after crush injury

…, CD Cristobal, CSE Lai, V Leyva-Aranda, HK Lee… - Biomaterials, 2021 - Elsevier
Multidomain peptide (MDP) hydrogels are a class of self-assembling materials that have been
shown to elicit beneficial responses for soft tissue regeneration. However, their capacity to …