Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells

TFJ Wagner, S Loch, S Lambert, I Straub… - Nature cell …, 2008 - nature.com
Transient receptor potential (TRP) cation channels are renowned for their ability to sense
diverse chemical stimuli. Still, for many members of this large and heterogeneous protein …

Fenamates as TRP channel blockers: mefenamic acid selectively blocks TRPM3

C Klose, I Straub, M Riehle, F Ranta… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Fenamates are N‐phenyl‐substituted anthranilic acid
derivatives clinically used as non‐steroid anti‐inflammatory drugs in pain treatment. Reports …

Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo

I Straub, U Krügel, F Mohr, J Teichert, O Rizun… - Molecular …, 2013 - ASPET
Transient receptor potential melastatin 3 (TRPM3) is a calcium-permeable nonselective cation
channel that is expressed in a subset of dorsal root (DRG) and trigeminal ganglia sensory …

[HTML][HTML] Primidone inhibits TRPM3 and attenuates thermal nociception in vivo

U Krügel, I Straub, H Beckmann, M Schaefer - Pain, 2017 - journals.lww.com
The melastatin-related transient receptor potential (TRP) channel TRPM3 is a nonselective
cation channel expressed in nociceptive neurons and activated by heat. Because TRPM3-…

P2X7 receptors at adult neural progenitor cells of the mouse subventricular zone

…, H Zimmermann, H Franke, W Nörenberg, I Straub… - …, 2013 - Elsevier
Neurogenesis requires the balance between the proliferation of newly formed progenitor cells
and subsequent death of surplus cells. RT-PCR and immunocytochemistry demonstrated …

Gradients in the mammalian cerebellar cortex enable Fourier-like transformation and improve storing capacity

I Straub, L Witter, A Eshra, M Hoidis, N Byczkowicz… - Elife, 2020 - elifesciences.org
Cerebellar granule cells (GCs) make up the majority of all neurons in the vertebrate brain, but
heterogeneities among GCs and potential functional consequences are poorly understood…

Experimental evaluation of earthworm and plant root soil penetration–cavity expansion models using cone penetrometer analogs

S Ruiz, I Straub, SJ Schymanski… - Vadose Zone …, 2016 - pubs.geoscienceworld.org
Recent mechanical models of soil penetration by earthworms and plant roots based on
penetration-cavity expansion were tested using cone penetration measurements at scales …

[HTML][HTML] Dendritic patch-clamp recordings from cerebellar granule cells demonstrate electrotonic compactness

I Delvendahl, I Straub, S Hallermann - Frontiers in Cellular …, 2015 - frontiersin.org
Cerebellar granule cells (GCs), the smallest neurons in the brain, have on average four short
dendrites that receive high-frequency mossy fiber inputs conveying sensory information. …

Loss of Piccolo function in rats induces cerebellar network dysfunction and pontocerebellar hypoplasia type 3-like phenotypes

…, C Bruns, S Hoffmann-Conaway, I Straub… - Journal of …, 2020 - Soc Neuroscience
Piccolo, a presynaptic active zone protein, is best known for its role in the regulated assembly
and function of vertebrate synapses. Genetic studies suggest a further link to several …

Gradients in the cerebellar cortex enable Fourier-like transformation and improve storing capacity

I Straub, L Witter, A Eshra, M Hoidis, N Byczkowicz… - bioRxiv, 2019 - biorxiv.org
Cerebellar granule cells (GCs) making up majority of all the neurons in the vertebrate brain,
but heterogeneities among GCs and potential functional consequences are poorly …