User profiles for J Nathans
Jeremy NathansProfessor of Molecular Biology and Genetics, Johns Hopkins University Verified email at jhmi.edu Cited by 42953 |
Tissue/planar cell polarity in vertebrates: new insights and new questions
Y Wang, J Nathans - 2007 - journals.biologists.com
This review focuses on the tissue/planar cell polarity (PCP) pathway and its role in generating
spatial patterns in vertebrates. Current evidence suggests that PCP integrates both global …
spatial patterns in vertebrates. Current evidence suggests that PCP integrates both global …
[PDF][PDF] The evolution and physiology of human color vision: insights from molecular genetic studies of visual pigments
J Nathans - Neuron, 1999 - cell.com
… structure of the red and green pigment genes (Nathans ceptor cells, and therefore the ratios
… green pigment gene array (Nathans et gene duplication event had placed the visual pigment …
… green pigment gene array (Nathans et gene duplication event had placed the visual pigment …
Macular degeneration: recent advances and therapeutic opportunities
The central retina mediates high acuity vision, and its progressive dysfunction due to
macular degeneration is the leading cause of visual disability among adults in industrialized …
macular degeneration is the leading cause of visual disability among adults in industrialized …
A new member of the frizzled family from Drosophila functions as a Wingless receptor
…, JC Hsieh, Y Wang, JP Macke, D Andrew, J Nathans… - Nature, 1996 - nature.com
… Scott and members of the Nathans and Nusse laboratories for discussions and comments
on the manuscript. MB was supported by a long-term fellowship from EMBO. These studies …
on the manuscript. MB was supported by a long-term fellowship from EMBO. These studies …
A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Starqardt macular dystrophy
…, Y Li, KL Anderson, RA Lewis, J Nathans… - Nature …, 1997 - nature.com
Stargardt disease (STGD, also known as fundus flavimaculatus; FFM) is an autosomal recessive
retinal disorder characterized by a juvenile-onset macular dystrophy, alterations of the …
retinal disorder characterized by a juvenile-onset macular dystrophy, alterations of the …
Molecular genetics of human color vision: the genes encoding blue, green, and red pigments
J Nathans, D Thomas, DS Hogness - Science, 1986 - science.org
Human color vision is based on three light-sensitive pigments. The isolation and sequencing
of genomic and complementary DNA clones that encode the apoproteins of these three …
of genomic and complementary DNA clones that encode the apoproteins of these three …
A new secreted protein that binds to Wnt proteins and inhibits their activites
… b–j, WIF-1 mRNAs detected by in situ hybridization. b–f, Xenopus; g–j, zebrafish. Expression
is first detectable at the onset of somitogenesis in paraxial mesoderm (b, g). Expression is …
is first detectable at the onset of somitogenesis in paraxial mesoderm (b, g). Expression is …
[HTML][HTML] Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair
… (J–L) Retinal flat mounts at P14 stained with GS-lectin and optically sectioned at the NFL (J),
outer edge of the IPL (K), and OPL (L). In the fz4 −/− retina, localized expansions develop …
outer edge of the IPL (K), and OPL (L). In the fz4 −/− retina, localized expansions develop …
Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa.
…, CH Sung, J Nathans… - Proceedings of the …, 1994 - National Acad Sciences
Retinitis pigmentosa (RP) is a group of inherited human diseases in which photoreceptor
degeneration leads to visual loss and eventually to blindness. Although mutations in the …
degeneration leads to visual loss and eventually to blindness. Although mutations in the …
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors
…, NA Jenkins, J Nathans - Proceedings of the …, 1997 - National Acad Sciences
This paper describes the identification of a new family of mammalian genes that encode
secreted proteins containing homology to the cysteine-rich ligand-binding domain found in the …
secreted proteins containing homology to the cysteine-rich ligand-binding domain found in the …