The genetics of early telencephalon patterning: some assembly required

JM Hébert, G Fishell - Nature Reviews Neuroscience, 2008 - nature.com
The immense range of human behaviours is rooted in the complex neural networks of the
cerebrum. The creation of these networks depends on the precise integration of specific …

Signaling pathways in reactive astrocytes, a genetic perspective

W Kang, JM Hébert - Molecular neurobiology, 2011 - Springer
Reactive astrocytes are associated with a vast array of central nervous system (CNS)
pathologies. The activation of astrocytes is characterized by changes in their molecular and …

Pharmacogenomics knowledge for personalized medicine

…, EM McDonagh, JM Hebert… - Clinical …, 2012 - Wiley Online Library
The Pharmacogenomics Knowledgebase (PharmGKB) is a resource that collects, curates,
and disseminates information about the impact of human genetic variation on drug responses. …

Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures

JM Hébert, SK McConnell - Developmental biology, 2000 - Elsevier
The use of genetics to study the development of the telencephalon and derivatives such as
the cerebral cortex has been limited. The telencephalon begins to form midway through …

[HTML][HTML] FGFR1 is required for the development of the auditory sensory epithelium

U Pirvola, J Ylikoski, R Trokovic, JM Hébert… - Neuron, 2002 - cell.com
The mammalian auditory sensory epithelium, the organ of Corti, comprises the hair cells and
supporting cells that are pivotal for hearing function. The origin and development of their …

[HTML][HTML] BMP signaling is required locally to pattern the dorsal telencephalic midline

JM Hébert, Y Mishina, SK McConnell - Neuron, 2002 - cell.com
BMPs have been proposed to pattern the medial-lateral axis of the telencephalon in a
concentration-dependent manner, thus helping to subdivide the embryonic telencephalon into …

FGF signaling through FGFR1 is required for olfactory bulb morphogenesis

JM Hébert, M Lin, J Partanen, J Rossant… - 2003 - journals.biologists.com
During development, the embryonic telencephalon is patterned into different areas that give
rise to distinct adult brain structures. Several secreted signaling molecules are expressed at …

mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation

JM Hébert, M Boyle, GR Martin - Development, 1991 - journals.biologists.com
During gastrulation in the mouse, the pluripotent embryonic ectoderm cells form the three
primary germ layers, ectoderm, mesoderm and endoderm. Little is known about the …

Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse

S Kawauchi, J Shou, R Santos, JM Hébert… - 2005 - journals.biologists.com
In vertebrate olfactory epithelium (OE), neurogenesis proceeds continuously, suggesting
that endogenous signals support survival and proliferation of stem and progenitor cells. We …

FGF signalling generates ventral telencephalic cells independently of SHH

…, HK Paek, K Yu, DM Ornitz, SK McConnell, JM Hébert - 2006 - journals.biologists.com
Sonic hedgehog (SHH) is required to generate ventral cell types throughout the central nervous
system. Its role in directly specifying ventral cells,however, has recently been questioned …