User profiles for J. N. Jovanovic
 | Jasmina N. JovanovicUCL School of Pharmacy Verified email at ucl.ac.uk Cited by 4686 |
Synapsins as mediators of BDNF-enhanced neurotransmitter release
JN Jovanovic, AJ Czernik, AA Fienberg… - Nature …, 2000 - nature.com
We examined enhancement of synaptic transmission by neurotrophins at the presynaptic
level. In a synaptosomal preparation, brain-derived neurotrophic factor (BDNF) increased …
level. In a synaptosomal preparation, brain-derived neurotrophic factor (BDNF) increased …
Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides
…, J Naslund, L Mazzarelli, G Fried, JN Jovanovic… - Nature medicine, 1998 - nature.com
Alzheimer's disease (AD) is characterized by the accumulation of cerebral plaques composed
of 40- and 42-amino acid β-amyloid (Aβ) peptides, and autosomal dominant forms of AD …
of 40- and 42-amino acid β-amyloid (Aβ) peptides, and autosomal dominant forms of AD …
Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.
JN Jovanovic, F Benfenati, YL Siow… - Proceedings of the …, 1996 - National Acad Sciences
The ability of neurotrophins to modulate the survival and differentiation of neuronal populations
involves the Trk/MAP (mitogen-activated protein kinase) kinase signaling pathway. More …
involves the Trk/MAP (mitogen-activated protein kinase) kinase signaling pathway. More …
Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons
JT Kittler, P Delmas, JN Jovanovic… - Journal of …, 2000 - Soc Neuroscience
Type A GABA receptors (GABA A ) mediate the majority of fast synaptic inhibition in the brain
and are believed to be predominantly composed of α, β, and γ subunits. Although changes …
and are believed to be predominantly composed of α, β, and γ subunits. Although changes …
Brain-derived neurotrophic factor modulates fast synaptic inhibition by regulating GABAA receptor phosphorylation, activity, and cell-surface stability
JN Jovanovic, P Thomas, JT Kittler… - Journal of …, 2004 - Soc Neuroscience
The efficacy of GABAergic synaptic inhibition is a principal factor in controlling neuronal
activity. We demonstrate here that brain-derived neurotrophic factor modulates the activity of …
activity. We demonstrate here that brain-derived neurotrophic factor modulates the activity of …
Phospho-dependent binding of the clathrin AP2 adaptor complex to GABAA receptors regulates the efficacy of inhibitory synaptic transmission
…, IL Arancibia-Carcamo, JN Jovanovic… - Proceedings of the …, 2005 - National Acad Sciences
The efficacy of synaptic inhibition depends on the number of γ-aminobutyric acid type A
receptors (GABA A Rs) expressed on the cell surface of neurons. The clathrin adaptor protein 2 (…
receptors (GABA A Rs) expressed on the cell surface of neurons. The clathrin adaptor protein 2 (…
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals
JN Jovanovic, TS Sihra, AC Nairn… - Journal of …, 2001 - Soc Neuroscience
Synapsins are major neuronal phosphoproteins involved in regulation of neurotransmitter
release. Synapsins are well established targets for multiple protein kinases within the nerve …
release. Synapsins are well established targets for multiple protein kinases within the nerve …
Multiple roles of protein kinases in the modulation of γ-aminobutyric acidA receptor function and cell surface expression
γ-Aminobutyric acid A (GABA A ) receptors are ligand-gated ion channels that mediate the
majority of fast synaptic inhibition in the brain and that are also important drug targets for …
majority of fast synaptic inhibition in the brain and that are also important drug targets for …
Generation and regulation of β‐amyloid peptide variants by neurons
Studies of processing of the Alzheimer β‐amyloid precursor protein (βAPP) have been
performed to date mostly in continuous cell lines and indicate the existence of two principal …
performed to date mostly in continuous cell lines and indicate the existence of two principal …
[HTML][HTML] Positive feedback regulation between γ-aminobutyric acid type A (GABAA) receptor signaling and brain-derived neurotrophic factor (BDNF) release in …
…, TS Sihra, SJ Moss, AM Thomson, JN Jovanovic - Journal of Biological …, 2011 - ASBMB
During the early development of the nervous system, γ-aminobutyric acid (GABA) type A
receptor (GABA A R)-mediated signaling parallels the neurotrophin/tropomyosin-related kinase (…
receptor (GABA A R)-mediated signaling parallels the neurotrophin/tropomyosin-related kinase (…