ABCA7 deficiency accelerates amyloid-β generation and Alzheimer's neuronal pathology

…, CC Liu, M Shinohara, J Frisch-Daiello… - Journal of …, 2016 - Soc Neuroscience
In Alzheimer's disease (AD), the accumulation and deposition of amyloid-β (Aβ) peptides in
the brain is a central event. Aβ is cleaved from amyloid precursor protein (APP) by β-…

APOE2 eases cognitive decline during Aging: Clinical and preclinical evaluations

…, Y Fu, L Price, JL FrischDaiello… - Annals of …, 2016 - Wiley Online Library
Objective Apolipoprotein E (apoE), a major cholesterol carrier in the brain, is associated with
a strong risk for Alzheimer disease. Compared to the risky APOE4 gene allele, the effects of …

Potential adverse effects of prolonged sevoflurane exposure on developing monkey brain: from abnormal lipid metabolism to neuronal damage

F Liu, SW Rainosek, JL Frisch-Daiello… - Toxicological …, 2015 - academic.oup.com
Sevoflurane is a volatile anesthetic that has been widely used in general anesthesia, yet its
safety in pediatric use is a public concern. This study sought to evaluate whether prolonged …

Improved butanol–methanol (BUME) method by replacing acetic acid for lipid extraction of biological samples

M Cruz, M Wang, J Frisch-Daiello, X Han - Lipids, 2016 - Springer
Extraction of lipids from biological samples is a critical step in lipidomics, especially for shotgun
lipidomics where lipid extracts are directly infused into a mass spectrometer. The butanol…

Hierarchical cluster analysis of ignitable liquids based on the total ion spectrum

EE Waddell, JL FrischDaiello… - Journal of forensic …, 2014 - Wiley Online Library
Gas chromatography–mass spectrometry (GC–MS) data of ignitable liquids in the Ignitable
Liquids Reference Collection (ILRC) database were processed to obtain 445 total ion spectra …

Lipidomics reveals a systemic energy deficient state that precedes neurotoxicity in neonatal monkeys after sevoflurane exposure

C Wang, F Liu, JL Frisch-Daiello, S Martin… - Analytica Chimica …, 2018 - Elsevier
Although numerous studies have raised public concerns regarding the safety of anesthetics
including sevoflurane in children, the biochemical mechanisms leading to anesthetics-…

Application of self-organizing feature maps to analyze the relationships between ignitable liquids and selected mass spectral ions

JL Frisch-Daiello, MR Williams, EE Waddell… - Forensic science …, 2014 - Elsevier
The unsupervised artificial neural networks method of self-organizing feature maps (SOFMs)
is applied to spectral data of ignitable liquids to visualize the grouping of similar ignitable …

Staff Advisory Council Meeting Minutes April 19, 2023

…, A Gabbard, D Gordon, P Kornegay, E Menna, J Sante… - 2023 - stars.library.ucf.edu
Note: Staff Council meets every third Wednesday of the month. Committees meet separately
and may pick their own meeting schedule day and times amongst their committee. Anyone …

GC/MS and DART-MS as complementary methods for investigating the effects of weathering on chemical profiles of ignitable liquids: A case study for paint thinner

S Perna, BM Dedicatoria, NS Chong, M Zhang - Forensic Chemistry, 2023 - Elsevier
In this study, gas chromatography/mass spectrometry (GC/MS) and direct analysis in real
time mass spectrometry (DART-MS) were used to analyze paint thinner samples weathered …

[HTML][HTML] Monkey business: the importance of mounting behavioural evidence for anaesthesia-induced developmental neurotoxicity

V Jevtovic-Todorovic - British Journal of Anaesthesia, 2018 - bjanaesthesia.org
A growing body of animal evidence from non-human primates focused on anaesthesia-induced
developmental neurotoxicity is rapidly becoming an invaluable source of information. …