Layer formation in the developing cerebral cortex requires the movement of neurons from
their site of origin to their final laminar position. We demonstrate, using time-lapse imaging of …

Inadequate physical fitness is a major problem affecting the function and health of children
with cerebral palsy (CP). Lack of optimal physical activity may contribute to the development …

Wingert JR, Burton H, Sinclair RJ, Brunstrom JE, Damiano DL. Joint-position sense and
kinesthesia in cerebral palsy. OBJECTIVES: To examine joint-position sense and kinesthesia in …

Motor deficits in cerebral palsy (CP) have been well documented; however, associated sensory
impairment in CP remains poorly understood. We examined tactile object recognition in …

Evidence from developmental, lesion, and neuroimaging studies indicates that the prefrontal
cortex plays a major role in executive abilities, including inhibitory control. Proficient …

The marginal zone (MZ) of embryonic neocortex is crucial to its normal development. We report
that neurotrophin-4 (but not NT3 or NGF), applied to embryonic rodent cortex in vitro or in …

The aim of this study was to determine the safety profile of high dose (15‐25 units/kg) of
botulinum toxin A (BTX‐A) in children with cerebral palsy (CP) and increased lower extremity …

Botulinum toxin A is commonly used to reduce spasticity and dystonia in children with
cerebral palsy. We report a pediatric patient who developed systemic botulism as a result of a …

Analysis of genetic mutations that lead to abnormal migration and layer formation in the
developing cerebral cortex of mice and humans has led to important new discoveries regarding …

The distribution of fibronectin (FN) changes rapidly during early development of the cerebral
cortex, but its cellular source is not known. Within situhybridization we find two spatially and …