User profiles for Jay A. Gottfried

Jay A. Gottfried

University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 12984

Encoding predictive reward value in human amygdala and orbitofrontal cortex

JA Gottfried, J O'Doherty, RJ Dolan - Science, 2003 - science.org
Adaptive behavior is optimized in organisms that maintain flexible representations of the
value of sensory-predictive cues. To identify central representations of predictive reward value …

Central mechanisms of odour object perception

JA Gottfried - Nature Reviews Neuroscience, 2010 - nature.com
The stimulus complexity of naturally occurring odours presents unique challenges for
central nervous systems that are aiming to internalize the external olfactory landscape. One …

Smell: central nervous processing

JA Gottfried - Taste and smell, 2006 - karger.com
This chapter focuses on central olfactory processing in the human brain. As the psychophysiology
of human olfactory function is important for appreciating its underlying neurophysiology…

[HTML][HTML] The nose smells what the eye sees: crossmodal visual facilitation of human olfactory perception

JA Gottfried, RJ Dolan - Neuron, 2003 - cell.com
Human olfactory perception is notoriously unreliable, but shows substantial benefits from
visual cues, suggesting important crossmodal integration between these primary sensory …

Aversive learning enhances perceptual and cortical discrimination of indiscriminable odor cues

W Li, JD Howard, TB Parrish, JA Gottfried - Science, 2008 - science.org
Learning to associate sensory cues with threats is critical for minimizing aversive experience.
The ecological benefit of associative learning relies on accurate perception of predictive …

Appetitive and aversive olfactory learning in humans studied using event-related functional magnetic resonance imaging

JA Gottfried, J O'Doherty, RJ Dolan - Journal of Neuroscience, 2002 - Soc Neuroscience
We combined event-related functional magnetic resonance imaging (fMRI) with olfactory
classical conditioning to differentiate the neural responses evoked during appetitive and …

[PDF][PDF] Olfactory predictive codes and stimulus templates in piriform cortex

C Zelano, A Mohanty, JA Gottfried - Neuron, 2011 - cell.com
Neuroscientific models of sensory perception suggest that the brain utilizes predictive codes
in advance of a stimulus encounter, enabling organisms to infer forthcoming sensory events…

Functional heterogeneity in human olfactory cortex: an event-related functional magnetic resonance imaging study

JA Gottfried, R Deichmann, JS Winston… - Journal of …, 2002 - Soc Neuroscience
Studies of patients with focal brain injury indicate that smell perception involves caudal
orbitofrontal and medial temporal cortices, but a more precise functional organization has not …

Human orbitofrontal cortex mediates extinction learning while accessing conditioned representations of value

JA Gottfried, RJ Dolan - Nature neuroscience, 2004 - nature.com
In extinction, an animal learns that a previously conditioned stimulus (CS+) no longer predicts
delivery of a salient reinforcer (unconditioned stimulus, UCS). Rodent studies indicate that …

Optimized EPI for fMRI studies of the orbitofrontal cortex

R Deichmann, JA Gottfried, C Hutton, R Turner - Neuroimage, 2003 - Elsevier
A common problem in gradient-echo echo planar imaging (EPI) is the occurrence of image
distortions and signal losses caused by susceptibility gradients near air/tissue interfaces. …