User profiles for Jayakumar Rajadas
Jayakumar RajadasFounding Director - ADDReB of Cardiovascular Institute , Stanford University and Prof. (Adjt … Verified email at stanford.edu Cited by 13241 |
Exosomes as nano-theranostic delivery platforms for gene therapy
Exosomes are biological membrane vesicles measuring 30 to 100nm. They contain an
abundance of small molecules like tetraspanins, receptors for targeting and adhesion, lipids, and …
abundance of small molecules like tetraspanins, receptors for targeting and adhesion, lipids, and …
Quantum dots and carbon nanotubes in oncology: a review on emerging theranostic applications in nanomedicine
Cancer is one of the main causes of death in the world, and according to the WHO it is projected
to continue rising. Current diagnostic modalities for the detection of cancer include the …
to continue rising. Current diagnostic modalities for the detection of cancer include the …
Nanomaterials engineering for drug delivery: a hybridization approach
The last twenty years have witnessed great advances in biology, medicine, and materials
science, leading to the development of various nanoparticle (NP)-mediated drug delivery …
science, leading to the development of various nanoparticle (NP)-mediated drug delivery …
[PDF][PDF] Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation
The highly conserved ubiquitin-proteasome system (UPS) controls the stability of most
nuclear and cytoplasmic proteins and is therefore essential for virtually all aspects of cellular …
nuclear and cytoplasmic proteins and is therefore essential for virtually all aspects of cellular …
[HTML][HTML] Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents
Brain-derived neurotrophic factor (BDNF) activates the receptor tropomyosin-related kinase
B (TrkB) with high potency and specificity, promoting neuronal survival, differentiation, and …
B (TrkB) with high potency and specificity, promoting neuronal survival, differentiation, and …
Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold
In this study, we examined the capacity of a biomimetic pullulan–collagen hydrogel to create
a functional biomaterial-based stem cell niche for the delivery of mesenchymal stem cells (…
a functional biomaterial-based stem cell niche for the delivery of mesenchymal stem cells (…
[PDF][PDF] Filamentous bacteriophage promote biofilm assembly and function
…, D Lazzareschi, E Katznelson, J Rajadas… - Cell host & …, 2015 - cell.com
Biofilms—communities of bacteria encased in a polymer-rich matrix—confer bacteria with
the ability to persist in pathologic host contexts, such as the cystic fibrosis (CF) airways. How …
the ability to persist in pathologic host contexts, such as the cystic fibrosis (CF) airways. How …
Blocking Macrophage Leukotriene B4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension
…, M Inayathullah, M Fridlib, J Rajadas… - Science translational …, 2013 - science.org
Pulmonary hypertension (PH) is a serious condition that affects mainly young and middle-aged
women, and its etiology is poorly understood. A prominent pathological feature of PH is …
women, and its etiology is poorly understood. A prominent pathological feature of PH is …
The effect of bioengineered acellular collagen patch on cardiac remodeling and ventricular function post myocardial infarction
…, A Wang, M Mahmoudi, AV Malkovskiy, J Rajadas… - Biomaterials, 2013 - Elsevier
Regeneration of the damaged myocardium is one of the most challenging fronts in the field
of tissue engineering due to the limited capacity of adult heart tissue to heal and to the …
of tissue engineering due to the limited capacity of adult heart tissue to heal and to the …
The p75 neurotrophin receptor promotes amyloid-β (1-42)-induced neuritic dystrophy in vitro and in vivo
JK Knowles, J Rajadas, TVV Nguyen… - Journal of …, 2009 - Soc Neuroscience
Oligomeric forms of amyloid-β (Aβ) are thought to play a causal role in Alzheimer's disease (AD),
and the p75 neurotrophin receptor (p75 NTR ) has been implicated in Aβ-induced …
and the p75 neurotrophin receptor (p75 NTR ) has been implicated in Aβ-induced …