Perinatal development of lumbar motoneurons and their inputs in the rat

L Vinay, F Brocard, JF Pflieger, J Simeoni-Alias… - Brain research …, 2000 - Elsevier
The rat is quite immature at birth and a rapid maturation of motor behavior takes place during
the first 2 postnatal weeks. Lumbar motoneurons undergo a rapid development during this …

Development of posture and locomotion: an interplay of endogenously generated activities and neurotrophic actions by descending pathways

…, F Clarac, JC Norreel, E Pearlstein, JF Pflieger - Brain Research …, 2002 - Elsevier
The adult pattern of locomotion is observed at the end of the second postnatal week in the
rat. The in vitro spinal cord isolated from immature rats has served as a valuable preparation …

Reversible disorganization of the locomotor pattern after neonatal spinal cord transection in the rat

JC Norreel, JF Pflieger, E Pearlstein… - Journal of …, 2003 - Soc Neuroscience
The central pattern generators (CPGs) for locomotion, located in the lumbar spinal cord, are
functional at birth in the rat. Their maturation occurs during the last few days preceding birth, …

Inhibitory postsynaptic potentials in lumbar motoneurons remain depolarizing after neonatal spinal cord transection in the rat

C Jean-Xavier, JF Pflieger… - Journal of …, 2006 - journals.physiology.org
GABA and glycine are excitatory in the immature spinal cord and become inhibitory during
development. The shift from depolarizing to hyperpolarizing inhibitory postsynaptic potentials (…

Perinatal development of the motor systems involved in postural control

…, F Clarac, C Jean-Xavier, E Pearlstein, JF Pflieger - Neural …, 2005 - hindawi.com
Motor behaviors of some species, such as the rat and the human baby, are quite immature
at birth. Here we review recent data on some of the mechanisms underlying the postnatal …

Postural modifications and neuronal excitability changes induced by a short-term serotonin depletion during neonatal development in the rat

JF Pflieger, F Clarac, L Vinay - Journal of Neuroscience, 2002 - Soc Neuroscience
Serotonin (5-HT) plays an important role both in the development and in the recovery of
locomotion after spinalization in vertebrates. We investigated the contribution of the serotonergic …

Picrotoxin and bicuculline have different effects on lumbar spinal networks and motoneurons in the neonatal rat

JF Pflieger, F Clarac, L Vinay - Brain research, 2002 - Elsevier
Bicuculline is the most commonly used GABA A receptor antagonist to investigate the contribution
of these receptors in motor control. However, this compound has been shown recently …

Anatomical study of vestibulospinal neurons in lampreys

N Bussières, JF Pflieger… - Journal of Comparative …, 1999 - Wiley Online Library
The present study was carried out to characterize anatomically the vestibulospinal (VS)
system of lampreys. Cobalt‐lysine or Texas Red dextran amines were applied in vitro to the …

Relationship between vestibular primary afferents and vestibulospinal neurons in lampreys

JF Pflieger, R Dubuc - Journal of Comparative Neurology, 2000 - Wiley Online Library
The distribution of vestibular primary afferents as well as their relationship with vestibulospinal
and other brainstem neurons were studied in lampreys using anatomical tracers. Afferents …

The vestibular primary afferents and the vestibulospinal projections in the developing and adult opossum, Monodelphis domestica

JF Pflieger, T Cabana - Anatomy and embryology, 1996 - Springer
The gray short-tailed opossum Monodelphis domestica is born in a very immature state (eyes
and ears closed, budlike hindlimbs, etc.) 14 days post-coitum, but it can locomote with its …