Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord

JW McDonald, XZ Liu, Y Qu, S Liu, SK Mickey… - Nature medicine, 1999 - nature.com
Transplantation approaches using cellular bridges 1, 2, fetal central nervous system cells 3,
4, 5, fibroblasts expressing neurotrophin-3 (ref. 6), hybridoma cells expressing inhibitory …

[HTML][HTML] Physiological and pathophysiological roles of excitatory amino acids during central nervous system development

JW McDonald, MV Johnston - Brain Research Reviews, 1990 - Elsevier
Recent studies suggest that excitatory amino acids (EAAs) have a wide variety of physiological
and pathophysiological roles during central nervous system (CNS) development. In …

Spinal-cord injury

JW McDonald, C Sadowsky - The Lancet, 2002 - thelancet.com
More than a decade ago, spinal-cord injury meant confinement to a wheelchair and a lifetime
of medical comorbidity. The physician's armamentarium of treatments was very limited, and …

Neuronal and glial apoptosis after traumatic spinal cord injury

…, R Hu, C Du, SX Zhang, JW McDonald… - Journal of …, 1997 - Soc Neuroscience
Cell death was examined by studying the spinal cords of rats subjected to traumatic insults
of mild to moderate severity. Within minutes after mild weight drop impact (a 10 gm weight …

Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation

…, TF Holekamp, JW McDonald - Proceedings of the …, 2000 - National Acad Sciences
Demyelination contributes to the loss of function consequent to central nervous system (CNS)
injury. Enhanced remyelination through transplantation of myelin-producing cells may offer …

Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity

JW Mcdonald, SP Althomsons, KL Hyrc, DW Choi… - Nature medicine, 1998 - nature.com
Little is known of the molecular mechanisms that trigger oligodendrocyte death and
demyelination in many acute central nervous system insults. Since oligodendrocytes express …

Socio-economic factors in infant and child mortality: a cross-national comparison

JN Hobcraft, JW McDonald, SO Rutstein - Population studies, 1984 - Taylor & Francis
In this paper five socio-economic correlates of infant and child mortality are considered
using results from World Fertility Survey enquiries in 28 developing countries. We consider …

Syntheses and characterization of ammonium and tetraalkylammonium thiomolybdates and thiotungstates

JW McDonald, GD Friesen, LD Rosenhein… - Inorganica Chimica …, 1983 - Elsevier
Improved methods for the preparation of [NH 4 ] 2 [MO 2 S 2 ] and [NH 4 ] 2 [MS 4 ] are
summarized and new syntheses of [NH 4 ] 2 [MOS 3 ] are reported (M = Mo, W). The facile …

Demographic determinants of infant and early child mortality: a comparative analysis

JN Hobcraft, JW McDonald, SO Rutstein - Population studies, 1985 - Taylor & Francis
In this paper we examine the relative importance of a number of demographic determinants
of infant and early child mortality using information from 39 World Fertility Survey countries. …

Synthesis of molybdenum (IV) and molybdenum (V) complexes using oxo abstraction by phosphines. Mechanistic implications

GJJ Chen, JW McDonald, WE Newton - Inorganic Chemistry, 1976 - ACS Publications
The reactions of the Mo (VI) compounds Mo02L2 (L= S2CNR2, S2PR2, cysteinato methyl
ester, acetylacetonato, 8-hydroxyquinolinato) with tertiary phosphines provides a convenient …