1. Whole‐cell currents were measured in outer hair cells isolated from each turn of the organ
of Corti of the guinea‐pig. 2. The slope input conductances at ‐70 mV of the cells ranged …

IT is thought that the sensitivity of mammalian hearing depends on amplification of the
incoming sound within the cochlea by a select population of sensory cells, the outer hair cells. It …

Hearing in mammals depends on a feedback process within the inner ear termed the ‘cochlear
amplifier’1. The essential components of this amplifier are sensorimotor cells, the outer …

Ribbon-type synapses in inner hair cells of the mammalian cochlea encode the complexity
of auditory signals by fast and tonic release through fusion of neurotransmitter-containing …

Mammalian auditory hair cells are few in number, experimentally inaccessible, and do not
proliferate postnatally or in vitro. Immortal cell lines with the potential to differentiate into …

Neural transmission of complex sounds demands fast and sustained rates of synaptic release
from the primary cochlear receptors, the inner hair cells (IHCs). The cells therefore require …

Key points Intercellular Ca 2+ waves are increases in cytoplasmic Ca 2+ levels that
propagate between cells. Periodic Ca 2+ waves have been linked to gene regulation and are …

A new cochlear modeling technique has been developed in which the number of assumptions
required in model formulation is significantly less than in previous modeling studies. The …

The kinetics of synaptic transfer from photoreceptors to second order neurons have been
determined in the retina of the snapping turtle. Analysis of the fluctuations resulting from the …

Recently, several reports have provided data about the way in which outer hair cells amplify
sound within the cochlea. These include new measurements of hair cell forces in the …