Cholinergic neurons in the basal forebrain and the brainstem form extensive projections to
a number of thalamic nuclei. Activation of cholinergic afferents during distinct behavioral …

Regulation of glutamate reuptake occurs along with several forms of synaptic plasticity.
These associations led to the hypothesis that regulation of glutamate uptake is a general …

Na + -dependent high-affinity glutamate transporters have important roles in the maintenance
of basal levels of glutamate and clearance of glutamate during synaptic transmission. …

Synchronous neuronal activity in the thalamocortical system is critical for a number of
behaviorally relevant computations, but hypersynchrony can limit information coding and lead to …

Long considered to fluctuate between pro‐ and anti‐inflammatory states, it has now become
evident that microglia occupy a variegated phenotypic landscape with relevance to aging …

… (c, d) MAGI-1 significantly reduced the cell surface expression of GLT-1 compared to the
expression of GLT-1 in HA plasmid transfected cells (**p < 0.01). MAGI-1 had no effect on cell …

Synaptic dysfunction is a hallmark of various neurodegenerative and neurodevelopmental
disorders. To interrogate synapse function in a systematic manner, we have established an …

Regulation of glutamate transporters often accompanies glutamatergic synaptic plasticity. We
investigated the mechanisms responsible for the increase in glutamate uptake associated …

The performance of neural codes to represent attributes of sensory signals has been
evaluated in the vertebrate peripheral and central nervous system. Here, we determine how …

The mechanistic Target of Rapamycin Complex 1 (mTORC1), a key regulator of protein
synthesis and cellular growth, is also required for long-term memory formation. Stimulation of …