Postadolescent changes in regional cerebral protein synthesis: an in vivo study in the FMR1 null mouse

M Qin, J Kang, TV Burlin, C Jiang… - Journal of …, 2005 - Soc Neuroscience
Methylation-induced transcriptional silencing of the fragile X mental retardation-1 (Fmr1)
gene leads to absence of the gene product, fragile X mental retardation protein (FMRP), and …

First Descriptions of blaKPC in Raoultella spp. (R. planticola and R. ornithinolytica): Report from the SENTRY Antimicrobial Surveillance Program

…, LM Deshpande, JR DiPersio, J Kang… - Journal of clinical …, 2009 - Am Soc Microbiol
Two strains of Raoultella planticola and one of Raoultella ornithinolytica showing carbapenem
resistance were recovered from patients hospitalized in New Jersey and Ohio. All …

[HTML][HTML] Teprotumumab for the treatment of chronic thyroid eye disease

S Ugradar, J Kang, AL Kossler, E Zimmerman, J Braun… - Eye, 2022 - nature.com
Background Teprotumumab, a novel IGF-1R antibody was recently shown to significantly
reduce the signs of active Thyroid eye disease (TED). The current study reviews its efficacy in …

Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation

M Qin, J Kang, CB Smith - Proceedings of the National …, 2002 - National Acad Sciences
In humans, failure to express the fragile X mental retardation protein (FMRP) gives rise to
fragile X syndrome, the most common form of inherited mental retardation. A fragile X knockout …

Replicable patterns of memory impairments in children with autism and their links to hyperconnected brain circuits

…, H Chang, J Rudoler, AB Al-Zughoul, JB Kang… - Biological Psychiatry …, 2023 - Elsevier
Background Memory impairments have profound implications for social communication and
educational outcomes in children with autism spectrum disorder (ASD). However, the …

Cerebral protein synthesis in a genetic mouse model of phenylketonuria

CB Smith, J Kang - Proceedings of the National Academy of …, 2000 - National Acad Sciences
Local rates of cerebral protein synthesis (lCPS leu ) were measured with the quantitative
autoradiographic [1- 14 C]leucine method in a genetic mouse model (Pah enu2 ) of …

Measurement of Regional Rates of Cerebral Protein Synthesis with L-[1-11C]leucine and PET with Correction for Recycling of Tissue Amino Acids: II. Validation in …

…, M Qin, TV Burlin, MP Cook, J Kang… - Journal of Cerebral …, 2005 - journals.sagepub.com
The confounding effect of recycling of amino acids derived from tissue protein breakdown into
the precursor pool for protein synthesis has been an obstacle to adapting in vivo methods …

Teprotumumab-related adverse events in thyroid eye disease: a multicenter study

…, CM Sears, KD Clauss, RD Rajjoub, JY Kang… - Ophthalmology, 2023 - Elsevier
Purpose To assess the duration, incidence, reversibility, and severity of adverse events (AEs)
in patients with thyroid eye disease (TED) treated with teprotumumab. Design Multicenter, …

Measurement of Regional Rates of Cerebral Protein Synthesis with L-[1-11C]Leucine and PET with Correction for Recycling of tissue amino acids: I. Kinetic Modeling …

KC Schmidt, MP Cook, M Qin, J Kang… - Journal of Cerebral …, 2005 - journals.sagepub.com
Measurements of regional rates of cerebral protein synthesis (rCPS) require correction for
the effect of recycling of tissue amino acids back into the precursor pool for protein synthesis. …

Change in lacrimal gland volume and aqueous tear production following treatment with teprotumumab

…, E Zimmerman, E Parunakian, J Kang… - Clinical & …, 2023 - Wiley Online Library
Background Dry eye syndrome occurs in up to 85% of patients with thyroid eye disease (TED).
Lacrimal gland enlargement correlates with subjective tearing and a reduction in quality …