User profiles for Junbing Wu
 | Junbing WuRutgers University Verified email at rutgers.edu Cited by 883 |
[HTML][HTML] Connectivity and functionality of the globus pallidus externa under normal conditions and Parkinson's disease
The globus pallidus externa (GPe) functions as a central hub in the basal ganglia for processing
motor and non-motor information through the creation of complex connections with the …
motor and non-motor information through the creation of complex connections with the …
The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death
Oxidative stress influences cell survival and homeostasis, but the mechanisms underlying
the biological effects of oxidative stress remain to be elucidated. The protein kinase MST1 (…
the biological effects of oxidative stress remain to be elucidated. The protein kinase MST1 (…
[HTML][HTML] Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction
Endocannabinoid (eCB), 2-arachidonoyl-glycerol (2-AG), the most abundant eCB in the
brain, regulates diverse neural functions. Here we linked multiple homozygous loss-of-function …
brain, regulates diverse neural functions. Here we linked multiple homozygous loss-of-function …
[HTML][HTML] MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation
Mammalian Sterile 20-like kinase 1 (MST1) protein kinase plays an important role in the
apoptosis induced by a variety of stresses. The MST1 is a serine/threonine kinase that is …
apoptosis induced by a variety of stresses. The MST1 is a serine/threonine kinase that is …
Leucine‐rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER–Golgi export
Leucine‐rich repeat kinase 2 ( LRRK 2) has been associated with Parkinson's disease ( PD
) and other disorders. However, its normal physiological functions and pathogenic properties …
) and other disorders. However, its normal physiological functions and pathogenic properties …
[PDF][PDF] Distinct connectivity and functionality of aldehyde dehydrogenase 1a1-positive nigrostriatal dopaminergic neurons in motor learning
Parkinson's disease causes the most profound loss of the aldehyde dehydrogenase 1A1-positive
(ALDH1A1 + ) nigrostriatal dopaminergic neuron (nDAN) subpopulation. The …
(ALDH1A1 + ) nigrostriatal dopaminergic neuron (nDAN) subpopulation. The …
[HTML][HTML] Phosphoinositide 3-Kinase/Akt Inhibits MST1-Mediated Pro-apoptotic Signaling through Phosphorylation of Threonine 120 2
Z Yuan, D Kim, S Shu, J Wu, J Guo, L Xiao… - Journal of biological …, 2010 - ASBMB
The protein kinase mammalian sterile 20-like kinase 1 (MST1) is a mammalian homologue
of the Drosophila hippo and plays a critical role in regulation of programmed cell death. …
of the Drosophila hippo and plays a critical role in regulation of programmed cell death. …
[HTML][HTML] Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway
Background Mammalian Ste20-like kinases (MSTs) are the mammalian homologue of
Drosophila hippo and play critical roles in regulation of cell death, organ size control, proliferation …
Drosophila hippo and play critical roles in regulation of cell death, organ size control, proliferation …
[HTML][HTML] c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82
Protein kinases play an important role in the maintenance of homeostasis between cell
survival and apoptosis. Deregulation of these kinases leads to various pathological …
survival and apoptosis. Deregulation of these kinases leads to various pathological …
Methylation-mediated regulation of E2F1 in DNA damage-induced cell death
E2F1 promotes DNA damage-induced apoptosis and the post-translational modifications of
E2F1 play an important role in the regulation of E2F1-mediated cell death. Here, we found …
E2F1 play an important role in the regulation of E2F1-mediated cell death. Here, we found …