BMP-7/OP-1, a member of the transforming growth factor-beta (TGF-beta) family of secreted
growth factors, is expressed during mouse embryogenesis in a pattern suggesting potential …

The 413.d insertional mutation arrests mouse development shortly after gastrulation. nodal,
a novel TGFb-related gene, is closely associated with the locus. The present study provides …

Coordinated production and remodeling of the extracellular matrix is essential during
development. It is of particular importance for skeletogenesis, as the ability of cartilage and bone to …

… three-dimensional reconstructions; Bob Coffey, Bill Polk and Robert McClure for use of the
Axiophot microscope and assistance with the imaging system; Riet Van der Meer and Karen …

Bone morphogenetic protein-2A (BMP-2A) is a member of the transforming growth factor β (TGF
β) gene family that has been implicated in cartilage and bone formation. Here we use in …

We have taken advantage of the sequence relationships among the bone morphogenetic
proteins (BMPs) to identify the mouse Bmp15 and human BMP15 genes. The 392-amino acid …

Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β (TGF-β)
superfamily. Many BMPs are produced in bone and show osteogenic activity, suggesting …

Bone morphogenetic protein-2 is a low molecular weight glycoprotein, classified as a
morphogen. The sine qua non of bone morphogenetic protein is consistently reproducible …

Previous studies have demonstrated the ability of bone morphogenetic proteins (BMPs) to
promote chondrogenic differentiation in vitro. However, the in vivo role of BMP signaling …

Members of the bone morphogenetic protein (BMP) class of transforming growth factor β (TGFβ)-related
molecules have been implicated in a variety of inductive processes throughout …