User profiles for Keith M. Sharrow
Keith SharrowChief, Bench Laboratory- DCI, William Beaumont Army Medical Center Verified email at mail.mil Cited by 1249 |
Calcineurin links Ca2+ dysregulation with brain aging
TC Foster, KM Sharrow, JR Masse… - Journal of …, 2001 - Soc Neuroscience
Brain aging is associated with altered Ca 2+ regulation. However, many Ca 2+ signal
transduction mechanisms have not been explored in the aged brain. Here, we report that cytosolic …
transduction mechanisms have not been explored in the aged brain. Here, we report that cytosolic …
Interaction of age and chronic estradiol replacement on memory and markers of brain aging
TC Foster, KM Sharrow, A Kumar, J Masse - Neurobiology of aging, 2003 - Elsevier
The current study examined effects of chronic estradiol replacement on cognition and biomarkers
of aging. Young, middle-aged, and aged rats were ovariectomized and implanted with …
of aging. Young, middle-aged, and aged rats were ovariectomized and implanted with …
Calcineurin as a potential contributor in estradiol regulation of hippocampal synaptic function
KM Sharrow, A Kumar, TC Foster - Neuroscience, 2002 - Elsevier
Estradiol influences Ca 2+ regulation and Ca 2+ -dependent synaptic plasticity, suggesting
estrogenic effects on Ca 2+ -dependent enzymes that regulate synaptic plasticity may …
estrogenic effects on Ca 2+ -dependent enzymes that regulate synaptic plasticity may …
Recovery from ischemic brain injury in the rat following a 10 h delayed injection with MLN519
AJ Williams, TM Myers, SI Cohn, KM Sharrow… - Pharmacology …, 2005 - Elsevier
In the present study, we evaluated delayed treatment effects of the proteasome inhibitor and
anti-inflammatory agent MLN519 (initiated 10 h post-injury) to improve recovery following …
anti-inflammatory agent MLN519 (initiated 10 h post-injury) to improve recovery following …
[BOOK][B] Acute estrogen (17B-estradiol) treatments ameliorate molecular and behavioral biomarkers of brain aging
KM Sharrow - 2002 - search.proquest.com
… By Keith Michael Sharrow … My mom and dad, Elizabeth and James Sharrow, for always
pushing me to go further and to never settle for second best. I am starting to understand, …
pushing me to go further and to never settle for second best. I am starting to understand, …
Cell surface antigenic characteristics of rat large granular lymphocytes (LGL)
…, T Barlozzari, RB Herberman, SO Sharrow… - NK Cells and Other …, 1982 - Elsevier
Publisher Summary This chapter examines cell-surface antigenic characteristics of rat large
granular lymphocytes (LGL). LGL have distinct azurophilic granules in their cytoplasm and …
granular lymphocytes (LGL). LGL have distinct azurophilic granules in their cytoplasm and …
Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment
EM Blalock, KC Chen, K Sharrow… - Journal of …, 2003 - Soc Neuroscience
Gene expression microarrays provide a powerful new tool for studying complex processes
such as brain aging. However, inferences from microarray data are often hindered by multiple …
such as brain aging. However, inferences from microarray data are often hindered by multiple …
Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived …
EA Grimm, KM Ramsey, A Mazumder… - The Journal of …, 1983 - rupress.org
Culture of human peripheral blood lymphocytes (PBL) in partially purified and lectin-free
interleukin 2 results in the generation of cytotoxic effector cells which have the unique property …
interleukin 2 results in the generation of cytotoxic effector cells which have the unique property …
[BOOK][B] NK cells and other natural effector cells
RB Herberman - 2012 - books.google.com
… Sharrow, Keith M. Ramsey, K0 Okumura, and Sonoko Habu … The Relation between Human
Natural Killer Cells and Interleukin-2 Wolfgang Domzig and Redo M. Stadler Modulation of …
Natural Killer Cells and Interleukin-2 Wolfgang Domzig and Redo M. Stadler Modulation of …
Recovery from and consequences of severe iatrogenic lymphopenia (induced to treat autoimmune diseases)
To ascertain the consequences of severe leukopenia and the tempo of recovery, we studied
the immunity of 56 adult patients treated for multiple sclerosis or systemic sclerosis with …
the immunity of 56 adult patients treated for multiple sclerosis or systemic sclerosis with …