Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …

In comparison to men, women initiate drug use at earlier ages and progress from initial use
to addiction more rapidly. This heightened intake and vulnerability to drugs of abuse is …

… Though the evidence for rapid, non-nuclear initiated action of ERα and ERβ had been
compelling for many years, the mechanism(s) by which these receptors signaled outside the …

Activation of the membrane estrogen receptor G-protein-coupled estrogen receptor (GPER)
in ovariectomized mice via the GPER agonist G-1 mimics the beneficial effects of 17β-…

The potent estrogen 17β-estradiol (E 2 ) is known to enhance hippocampal memory and
plasticity, however the molecular mechanisms underlying these effects remain unclear. Brain …

Hippocampal plasticity and memory are modulated by the potent estrogen 17β-estradiol (E
2 ). Research on the molecular mechanisms of hippocampal E 2 signaling has uncovered …

The ubiquitin proteasome system (UPS) is a primary mechanism through which proteins are
degraded in cells. UPS activity in the dorsal hippocampus (DH) is necessary for multiple …

As the non-nuclear initiated effects of steroid hormone signaling have become more widely
accepted, there has been a need to define the novel mechanisms of hormone receptor action …

The group I metabotropic glutamate receptors (mGluR1a and mGluR5) are important modulators
of neuronal structure and function. Although these receptors share common signaling …

Gonadal hormones play a vital role in driving motivated behavior. They not only modulate
responses to naturally rewarding stimuli, but also influence responses to drugs of abuse. A …