The impact of coronavirus disease 2019 (COVID-19) on healthcare-associated infections

…, L Goldin, A Isaacs, K Kleja, KM Korwek… - Clinical Infectious …, 2022 - academic.oup.com
Background The profound changes wrought by coronavirus disease 2019 (COVID-19) on
routine hospital operations may have influenced performance on hospital measures, including …

Cognitive disruption and altered hippocampus synaptic function in Reelin haploinsufficient mice

S Qiu, KM Korwek, AR Pratt-Davis, M Peters… - Neurobiology of learning …, 2006 - Elsevier
The heterozygote reeler mouse (HRM) shows many neuroanatomical and biochemical features
that are also present in some human cognitive disorders, such as schizophrenia. In the …

Differential reelin-induced enhancement of NMDA and AMPA receptor activity in the adult hippocampus

S Qiu, LF Zhao, KM Korwek… - Journal of Neuroscience, 2006 - Soc Neuroscience
The developmental lamination of the hippocampus and other cortical structures requires a
signaling cascade initiated by reelin and its receptors, apoER2 (apolipoprotein E receptor 2) …

Reelin, very-low-density lipoprotein receptor, and apolipoprotein E receptor 2 control somatic NMDA receptor composition during hippocampal maturation in vitro

…, D Verrier, D Frankova, KM Korwek… - Journal of …, 2005 - Soc Neuroscience
Reelin is a secreted protein that regulates brain layer formation during embryonic development.
Reelin binds several receptors, including two members of the low-density lipoprotein (…

[HTML][HTML] ApoE isoform-dependent changes in hippocampal synaptic function

KM Korwek, JH Trotter, MJ LaDu, PM Sullivan… - Molecular …, 2009 - Springer
The lipoprotein receptor system in the hippocampus is intimately involved in the modulation
of synaptic transmission and plasticity. The association of specific apoE isoform expression …

Data-driven process and operational improvement in the emergency department: the ED Dashboard and Reporting Application

…, JD Englebright, D Cheung, KM Korwek… - Journal of Healthcare …, 2012 - journals.lww.com
Emergency departments (EDs) in the United States are expected to provide consistent, high-quality
care to patients. Unfortunately, EDs are encumbered by problems associated with …

Patient characteristics and admitting vital signs associated with coronavirus disease 2019 (COVID-19)–related mortality among patients admitted with noncritical …

…, RP Wenzel, LE McLean, KM Korwek… - Infection Control & …, 2021 - cambridge.org
Objective:To determine risk factors for mortality among COVID-19 patients admitted to a system
of community hospitals in the United States.Design:Retrospective analysis of patient data …

A fresh look at an ancient receptor family: emerging roles for low density lipoprotein receptors in synaptic plasticity and memory formation

S Qiu, KM Korwek, EJ Weeber - Neurobiology of learning and memory, 2006 - Elsevier
The well-known family of low-density lipoprotein receptors represents a collection of ancient
membrane receptors that have been remarkably conserved throughout evolution. These …

Hyperglycaemia increases mortality risk in non‐diabetic patients with COVID‐19 even more than in diabetic patients

J Morse, W Gay, KM Korwek, LE McLean… - Endocrinology …, 2021 - Wiley Online Library
Aim Diabetes has been identified as a risk factor for poor outcomes in patients with COVID‐19.
We examined the association of hyperglycaemia, both in the presence and absence of …

The effect of endogenous dopamine in rotenone-induced toxicity in PC12 cells

AA Dukes, KM Korwek, TG Hastings - Antioxidants & redox signaling, 2005 - liebertpub.com
Deficiencies in Complex I have been observed in Parkinson's disease (PD) patients.
Systemic exposure to rotenone, a Complex I inhibitor, has been shown to lead to selective …