The amount and availability of proteins are regulated by their synthesis, degradation, and
transport. These processes can specifically, locally, and temporally regulate a protein or a …

Brain-derived neurotrophic factor (BDNF) is implicated in long-term synaptic plasticity in the
adult hippocampus, but the cellular mechanisms are little understood. Here we used …

One of the hallmarks of learning processes in any species studied so far is that they require
intact protein synthesis machinery in order to consolidate memories. Interestingly, synaptic …

Conditioned taste aversion (CTA) is an associative learning paradigm, wherein consumption
of an appetitive tastant (eg, saccharin) is paired to the administration of a malaise-inducing …

The late phase of long-term potentiation (LTP) and memory (LTM) requires new gene expression,
but the molecular mechanisms that underlie these processes are not fully understood. …

Increasing evidence indicates that the brain regulates peripheral immunity, yet whether and
how the brain represents the state of the immune system remains unclear. Here, we show …

Glycogen synthase kinase‐3 (GSK‐3) is a serine/threonine kinase regulating diverse cellular
functions including metabolism, transcription and cell survival. Numerous intracellular …

Application of the protein synthesis inhibitor anisomycin to the rat gustatory cortex before
and during training impairs conditioned taste aversion (CTA) to saccharin. No behavioral …

Aging is a major risk factor for many diseases including metabolic syndrome, cancer,
inflammation, and neurodegeneration. Identifying mechanistic common denominators underlying …

Rats were given to drink an unfamiliar taste solution under conditions that result in long-term
memory of that taste. The insular cortex, which contains the taste cortex, was then removed …