User profiles for Kodi S. Ravichandran
Kodi RavichandranWashington University School of Medicine Verified email at wustl.edu Cited by 28859 |
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
…, JJ Lysiak, TK Harden, N Leitinger, KS Ravichandran - Nature, 2009 - nature.com
Phagocytic removal of apoptotic cells occurs efficiently in vivo such that even in tissues with
significant apoptosis, very few apoptotic cells are detectable 1 . This is thought to be due to …
significant apoptosis, very few apoptotic cells are detectable 1 . This is thought to be due to …
Pannexin 1 channels mediate 'find-me'signal release and membrane permeability during apoptosis
Apoptotic cells release ‘find-me’ signals at the earliest stages of death to recruit phagocytes
1 . The nucleotides ATP and UTP represent one class of find-me signals 2 , but their …
1 . The nucleotides ATP and UTP represent one class of find-me signals 2 , but their …
Engulfment of apoptotic cells: signals for a good meal
KS Ravichandran, U Lorenz - Nature Reviews Immunology, 2007 - nature.com
The clearance of apoptotic cells by phagocytes is an integral component of normal life, and
defects in this process can have significant implications for self tolerance and autoimmunity. …
defects in this process can have significant implications for self tolerance and autoimmunity. …
Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums
KS Ravichandran - Journal of Experimental Medicine, 2010 - rupress.org
Everyday we turnover billions of cells. The quick, efficient, and immunologically silent disposal
of the dying cells requires a coordinated orchestration of multiple steps, through which …
of the dying cells requires a coordinated orchestration of multiple steps, through which …
Apoptotic cell clearance: basic biology and therapeutic potential
The prompt removal of apoptotic cells by phagocytes is important for maintaining tissue
homeostasis. The molecular and cellular events that underpin apoptotic cell recognition and …
homeostasis. The molecular and cellular events that underpin apoptotic cell recognition and …
Clearance of apoptotic cells: implications in health and disease
MR Elliott, KS Ravichandran - Journal of Cell Biology, 2010 - rupress.org
Recent advances in defining the molecular signaling pathways that regulate the phagocytosis
of apoptotic cells have improved our understanding of this complex and evolutionarily …
of apoptotic cells have improved our understanding of this complex and evolutionarily …
[PDF][PDF] Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways
KS Ravichandran - Immunity, 2011 - cell.com
Prompt and efficient clearance of apoptotic cells is necessary to prevent secondary necrosis
of dying cells and to avoid immune responses to autoantigens. Recent studies have shed …
of dying cells and to avoid immune responses to autoantigens. Recent studies have shed …
[HTML][HTML] Phagocytosis of apoptotic cells in homeostasis
S Arandjelovic, KS Ravichandran - Nature immunology, 2015 - nature.com
Human bodies collectively turn over about 200 billion to 300 billion cells every day. Such
turnover is an integral part of embryonic and postnatal development, as well as routine tissue …
turnover is an integral part of embryonic and postnatal development, as well as routine tissue …
Phagosome maturation: going through the acid test
JM Kinchen, KS Ravichandran - Nature reviews Molecular cell biology, 2008 - nature.com
Phagosome maturation is the process by which internalized particles (such as bacteria and
apoptotic cells) are trafficked into a series of increasingly acidified membrane-bound …
apoptotic cells) are trafficked into a series of increasingly acidified membrane-bound …
Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestion
…, KS Ravichandran - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Clearance of apoptotic cells is the final stage of programmed cell death. Uncleared corpses
can become secondarily necrotic, promoting inflammation and autoimmunity. Remarkably, …
can become secondarily necrotic, promoting inflammation and autoimmunity. Remarkably, …