User profiles for L. Coutellier
Laurence CoutellierThe Ohio State University Verified email at osu.edu Cited by 1880 |
Prefrontal excitatory/inhibitory balance in stress and emotional disorders: evidence for over-inhibition
CE Page, L Coutellier - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Chronic stress-induced emotional disorders like anxiety and depression involve imbalances
between the excitatory glutamatergic system and the inhibitory GABAergic system in the …
between the excitatory glutamatergic system and the inhibitory GABAergic system in the …
Sex differences in risk and resilience: stress effects on the neural substrates of emotion and motivation
Risk for stress-sensitive psychopathologies differs in men and women, yet little is known about
sex-dependent effects of stress on cellular structure and function in corticolimbic regions …
sex-dependent effects of stress on cellular structure and function in corticolimbic regions …
A dramatic increase of C1q protein in the CNS during normal aging
…, DA Fraser, EA Lovelett, L Coutellier, L Kim… - Journal of …, 2013 - Soc Neuroscience
… L, M, C1q immunoreactivity dramatically increased with age in synaptic layers of the human
hippocampus. L, C1q immunoreactivity in the human infant (2-month-old) was restricted to …
hippocampus. L, C1q immunoreactivity in the human infant (2-month-old) was restricted to …
Age-and sex-specific effects of stress on parvalbumin interneurons in preclinical models: Relevance to sex differences in clinical neuropsychiatric and …
EM Woodward, L Coutellier - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Stress is a major risk factor for neurodevelopmental and neuropsychiatric disorders, with the
capacity to impact susceptibility to disease as well as long-term neurobiological and …
capacity to impact susceptibility to disease as well as long-term neurobiological and …
Pig's responses to repeated social regrouping and relocation during the growing-finishing period
L Coutellier, C Arnould, A Boissy, P Orgeur… - Applied animal …, 2007 - Elsevier
In animal husbandry, pigs have to cope with social challenges when regrouped with unfamiliar
conspecifics. Regrouping pigs may result in an acute stress and physical injuries thus …
conspecifics. Regrouping pigs may result in an acute stress and physical injuries thus …
[HTML][HTML] Npas4: a neuronal transcription factor with a key role in social and cognitive functions relevant to developmental disorders
L Coutellier, S Beraki, PM Ardestani, NL Saw… - 2012 - journals.plos.org
Npas4 is a transcription factor, which is highly expressed in the brain and regulates the
formation and maintenance of inhibitory synapses in response to excitatory synaptic activity. A …
formation and maintenance of inhibitory synapses in response to excitatory synaptic activity. A …
Sensitivity of the prefrontal GABAergic system to chronic stress in male and female mice: relevance for sex differences in stress-related disorders
R Shepard, CE Page, L Coutellier - Neuroscience, 2016 - Elsevier
Stress-induced modifications of the prefrontal cortex (PFC) are believed to contribute to the
onset of mood disorders, such as depression and anxiety, which are more prevalent in …
onset of mood disorders, such as depression and anxiety, which are more prevalent in …
Changes in the prefrontal glutamatergic and parvalbumin systems of mice exposed to unpredictable chronic stress
R Shepard, L Coutellier - Molecular neurobiology, 2018 - Springer
The prefrontal cortex (PFC) is highly sensitive to the effects of stress, a known risk factor of
mood disorders including anxiety and depression. Abnormalities in PFC functioning have …
mood disorders including anxiety and depression. Abnormalities in PFC functioning have …
[HTML][HTML] Prefrontal parvalbumin cells are sensitive to stress and mediate anxiety-related behaviors in female mice
Reduced activity of the prefrontal cortex (PFC) is seen in mood disorders including depression
and anxiety. The mechanisms of this hypofrontality remain unclear. Because of their …
and anxiety. The mechanisms of this hypofrontality remain unclear. Because of their …
Adolescent stress disrupts the maturation of anxiety-related behaviors and alters the developmental trajectory of the prefrontal cortex in a sex-and age-specific manner
CE Page, L Coutellier - Neuroscience, 2018 - Elsevier
Adolescence is a window of vulnerability to environmental factors such as chronic stress that
can disrupt brain development and cause long-lasting behavioral dysfunction, as seen in …
can disrupt brain development and cause long-lasting behavioral dysfunction, as seen in …