User profiles for Luke S. Watson
Luke S. WatsonMedical Scientist (Consultant), Sage Therapeutics Verified email at sagerx.com Cited by 190 |
[HTML][HTML] Obesity-related cognitive impairment: The role of endothelial dysfunction
Obesity is a global pandemic associated with macro- and microvascular endothelial dysfunction.
Microvascular endothelial dysfunction has recently emerged as a significant risk factor …
Microvascular endothelial dysfunction has recently emerged as a significant risk factor …
[HTML][HTML] Neuronally derived extracellular vesicles: an emerging tool for understanding Alzheimer's disease
LS Watson, ED Hamlett, TD Stone… - Molecular …, 2019 - Springer
In order for Alzheimer’s disease (AD) to manifest, cells must communicate “pathogenic material”
such as proteins, signaling molecules, or genetic material to ensue disease propagation…
such as proteins, signaling molecules, or genetic material to ensue disease propagation…
Lumateperone normalizes pathological levels of acute inflammation through important pathways known to be involved in mood regulation
Lumateperone is indicated for the treatment of schizophrenia in adults and for depressive
episodes associated with bipolar I or II disorder (bipolar depression) in adults, as monotherapy …
episodes associated with bipolar I or II disorder (bipolar depression) in adults, as monotherapy …
Hyperinsulinemia alters insulin receptor presentation and internalization in brain microvascular endothelial cells
LS Watson, B Wilken-Resman… - Diabetes and …, 2022 - journals.sagepub.com
Insulin receptors are internalized by endothelial cells to facilitate their physiological processes;
however, the impact of hyperinsulinemia in brain endothelial cells is not known. Thus, the …
however, the impact of hyperinsulinemia in brain endothelial cells is not known. Thus, the …
Quantification by luminescence tracking of red emissive gold nanoparticles in cells
AN Dosumu, S Claire, LS Watson, PM Girio… - JACS Au, 2021 - ACS Publications
Optical microscopy techniques are ideal for live cell imaging for real-time nanoparticle tracking
of nanoparticle localization. However, the quantification of nanoparticle uptake is usually …
of nanoparticle localization. However, the quantification of nanoparticle uptake is usually …
Operant conditioning in toilet training severely mentally retarded boys.
M Hundziak, RA Maurer, LS Watson - American Journal of Mental …, 1965 - psycnet.apa.org
29 severely retarded boys, with IQs ranging from 8-33 and CAs 7-14 and free from major
physical handicaps were selected for a controlled study designed to test the efficacy of operant …
physical handicaps were selected for a controlled study designed to test the efficacy of operant …
High-Fat diet impairs tactile discrimination memory in the mouse
LS Watson, TD Stone, D Williams, AS Williams… - Behavioural brain …, 2020 - Elsevier
Research on the impact of diet and memory has garnered considerable attention while
exploring the link between obesity and cognitive impairment. High-fat diet (HFD) rodent models …
exploring the link between obesity and cognitive impairment. High-fat diet (HFD) rodent models …
The elimination of the self-destructive behavior of a psychotic child: A case study
DT Saposnek, LS Watson Jr - Behavior Therapy, 1974 - Elsevier
A treatment procedure derived from Zaslow's “rage-reduction” technique was explored as a
method for eliminating severe chronic head-slapping behavior of an institutionalized …
method for eliminating severe chronic head-slapping behavior of an institutionalized …
A program for teaching behavior modification skills to institutional staff
LS Watson Jr, R Uzzell - Applied Research in Mental Retardation, 1980 - Elsevier
A training program that utilized Backward Chaining to teaching self-help skills was employed
with paraprofessional staff in three residential facilities for the mentally retarded. Two …
with paraprofessional staff in three residential facilities for the mentally retarded. Two …
Teaching self-help skills to the mentally retarded
LS Watson Jr, R Uzzell - Handbook of behavior modification with the …, 1981 - Springer
The behavior modification (operant) approach to teaching independent living skills is a relatively
new technology that has been in existence for approximately fifteen years. Antecedents …
new technology that has been in existence for approximately fifteen years. Antecedents …