L’auteur propose d’analyser certaines conduites agies et langagières d’enfants et d’adolescents,
qui présentent des difficultés de compréhension. Il apparaît que ceux-ci mobilisent une …

Perisynaptic astrocytes express important glutamate transporters, especially excitatory amino
acid transporter 2 (EAAT2, rodent analog GLT1) to regulate extracellular glutamate levels …

The molecular signature and functional properties of astroglial subtypes in the adult CNS
remain largely undefined. By using translational ribosome affinity purification followed by RNA-…

In mammalians, toll-like receptors (TLR) signal-transduction pathways induce the expression
of a variety of immune-response genes, including inflammatory cytokines. It is therefore …

Functional maturation of astroglia is characterized by the development of a unique, ramified
morphology and the induction of important functional proteins, such as glutamate transporter …

Recent studies have implicated potentially significant roles for astrocytes in the pathogenesis
of neurodevelopmental disorders. Astrocytes undergo a dramatic maturation process …

How the loss of fragile X mental retardation protein (FMRP) in different brain cell types, especially
in non-neuron glial cells, induces fragile X syndrome (FXS) phenotypes has just begun …

Spinocerebellar ataxia 7 (SCA7) is a neurodegenerative disease caused by a polyglutamine
(polyQ) expansion in the ataxin 7 (ATXN7) protein, a member of a multiprotein complex …

Motor neurons are progressively and predominantly degenerated in ALS, which is not only
induced by multiple intrinsic pathways but also significantly influenced by the neighboring …

Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by the loss-of-function
of fragile X mental retardation protein (FMRP). The loss of FMRP function in neurons …