User profiles for Manuel Alvarez-Dolado
Manuel Alvarez-DoladoCSIC Tenure Scientist Verified email at cabimer.es Cited by 4652 |
Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes
Recent studies have suggested that bone marrow cells possess a broad differentiation
potential, being able to form new liver cells, cardiomyocytes and neurons 1 , 2 . Several groups …
potential, being able to form new liver cells, cardiomyocytes and neurons 1 , 2 . Several groups …
[PDF][PDF] Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex
Dendrite branching and spine formation determines the function of morphologically distinct
and specialized neuronal subclasses. However, little is known about the programs instructing …
and specialized neuronal subclasses. However, little is known about the programs instructing …
Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain
M Alvarez-Dolado, ME Calcagnotto… - Journal of …, 2006 - Soc Neuroscience
Embryonic medial ganglionic eminence (MGE) cells transplanted into the adult brain can
disperse, migrate, and differentiate to neurons expressing GABA, the primary inhibitory …
disperse, migrate, and differentiate to neurons expressing GABA, the primary inhibitory …
[PDF][PDF] Nav1. 1-overexpressing interneuron transplants restore brain rhythms and cognition in a mouse model of Alzheimer's disease
…, I Cobos, K Ho, L Gan, L Mucke, M Alvarez-Dolado… - Neuron, 2018 - cell.com
Inhibitory interneurons regulate the oscillatory rhythms and network synchrony that are required
for cognitive functions and disrupted in Alzheimer's disease (AD). Network dysrhythmias …
for cognitive functions and disrupted in Alzheimer's disease (AD). Network dysrhythmias …
Thyroid hormone regulates reelin and dab1expression during brain development
M Alvarez-Dolado, M Ruiz, JA Del Rıo… - Journal of …, 1999 - Soc Neuroscience
The reelin and dab1 genes are necessary for appropriate neuronal migration and lamination
during brain development. Since these processes are controlled by thyroid hormone, we …
during brain development. Since these processes are controlled by thyroid hormone, we …
Dlx-dependent and-independent regulation of olfactory bulb interneuron differentiation
JE Long, S Garel, M Alvarez-Dolado… - Journal of …, 2007 - Soc Neuroscience
Olfactory bulb interneuron development is a complex multistep process that involves cell
specification in the ventral telencephalon, tangential migration into the olfactory bulb, and local …
specification in the ventral telencephalon, tangential migration into the olfactory bulb, and local …
Specific contribution of Reelin expressed by Cajal–Retzius cells or GABAergic interneurons to cortical lamination
…, M Pascual, M Álvarez-Dolado… - Proceedings of the …, 2022 - National Acad Sciences
The extracellular protein Reelin, expressed by Cajal–Retzius (CR) cells at early stages of
cortical development and at late stages by GABAergic interneurons, regulates radial migration …
cortical development and at late stages by GABAergic interneurons, regulates radial migration …
Transplant of GABAergic precursors restores hippocampal inhibitory function in a mouse model of seizure susceptibility
…, M Piquer-Gil, LE Mello, M Álvarez-Dolado - Cell …, 2010 - journals.sagepub.com
Defects in GABAergic function can cause epilepsy. In the last years, cell-based therapies
have attempted to correct these defects with disparate success on animal models of epilepsy. …
have attempted to correct these defects with disparate success on animal models of epilepsy. …
Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult …
…, M Martínez-Losa, M Álvarez-Dolado… - Disease models & …, 2017 - journals.biologists.com
Cocaine addiction disorder is notably aggravated by concomitant cognitive and emotional
pathology that impedes recovery. We studied whether a persistent cognitive/emotional …
pathology that impedes recovery. We studied whether a persistent cognitive/emotional …
[HTML][HTML] Human mesenchymal stem cells prevent neurological complications of radiotherapy
…, E López, JA Barcia, M Alvarez-Dolado… - Frontiers in cellular …, 2019 - frontiersin.org
Radiotherapy is a highly effective tool for the treatment of brain cancer. However, radiation
also causes detrimental effects in the healthy tissue, leading to neurocognitive sequelae that …
also causes detrimental effects in the healthy tissue, leading to neurocognitive sequelae that …