Intermittent intense ultraviolet (UV) exposure represents an important aetiological factor in
the development of malignant melanoma 1 . The ability of UV radiation to cause tumour-…

Laminins are heterotrimeric molecules composed of an α, a β, and a γ chain; they have broad
functional roles in development and in stabilizing epithelial structures. Here, we identified …

Collagens are the most abundant proteins in the human body, important in maintenance of
tissue structure and hemostasis. Here we report that collagens are high affinity ligands for the …

Components of the extracellular matrix exert myriad effects on tissues throughout the body.
In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, have been …

Normal tissue function requires adequate supply of oxygen through blood vessels. Understanding
how blood vessels form is a challenging objective because angiogenesis is vital to …

The SARS-CoV-2 pandemic has unprecedented implications for public health, social life,
and the world economy. Because approved drugs and vaccines are limited or not available, …

Here we describe a novel collagen belonging to the class of von Willebrand factor A (VWA)
domain-containing proteins. This novel protein was identified by screening the EST data …

Innate immunity triggers responsible for viral control or hyperinflammation in COVID‐19 are
largely unknown. Here we show that the SARS‐CoV‐2 spike protein (S‐protein) primes …

Chronic wounds associated with vascular disease, diabetes mellitus, or aging are leading
causes of morbidity in western countries and represent an unresolved clinical problem. The …

Interstitial collagen fibrils form the supporting scaffold of all connective tissues. The synthesis
of this framework is subject to a precise spatial and temporal regulation in order to meet the …