Melanocortin receptor accessory proteins (MRAPs) modulate signaling of melanocortin
receptors in vitro. To investigate the physiological role of brain-expressed melanocortin 2 …

New neurons, continuously added in the adult olfactory bulb (OB) and hippocampus, are
involved in information processing in neural circuits. Here, we show that synaptic pruning of …

Obesity is characterized by massive adipose tissue accumulation and is associated with
psychiatric disorders and cognitive impairment in human and animal models. However, it is …

A search for production of the superheavy elements with atomic numbers 119 and 120 was
performed in the Ti 50+ Bk 249 and Ti 50+ Cf 249 fusion-evaporation reactions, respectively, …

Experimental investigations of transactinoide elements provide benchmark results for
chemical theory and probe the predictive power of trends in the periodic table. So far, in gas-phase …

A long-standing paradigm posits that hypothalamic corticotropin-releasing hormone (CRH)
regulates neuroendocrine functions such as adrenal glucocorticoid release, whereas extra-…

Synaptic plasticity in hippocampal neurons has been thought to represent a variety of memories.
Although accumulating evidence indicates a crucial role of BDNF/TrkB/Akt signaling in …

Bone marrow-derived mesenchymal stromal cells (BM-MSCs) in culture are derived from BM
stromal cells or skeletal stem cells. Whereas MSCs have been exploited in clinical medicine…

Dishevelled is the common mediator of canonical and non-canonical Wnt signalling
pathways, which are important for embryonic development, tissue maintenance and cancer …

Context: Initiating factors leading to production of adrenal androgens are poorly defined.
Cortisol is present in high concentrations within the adrenal gland, and its production rises with …