Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa

…, S Siegert, AC Groner, E Cabuy, V Forster, M Seeliger… - science, 2010 - science.org
Retinitis pigmentosa refers to a diverse group of hereditary diseases that lead to incurable
blindness, affecting two million people worldwide. As a common pathology, rod …

[PDF][PDF] Standard for clinical electroretinography (2004 update)

MF Marmor, GE Holder, MW Seeliger… - Documenta …, 2004 - iscev.org
For the International Society for Clinical Electrophysiology of Vision 1Department of
Ophthalmology, Stanford University School of Medicine, Stanford, CA, USA; 2Department of …

HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

…, A Wenzel, M Groszer, H Mayser, M Seeliger… - Nature medicine, 2002 - nature.com
Erythropoietin (Epo) is upregulated by hypoxia and provides protection against apoptosis of
erythroid progenitors in bone marrow and brain neurons. Here we show in the adult mouse …

Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

…, EC Bryda, K Kutsche, HG Nothwang, M Seeliger… - Nature …, 2001 - nature.com
Usher syndrome type I (USH1) is an autosomal recessive disorder characterized by congenital
sensorineural hearing loss, vestibular dysfunction and visual impairment due to early …

Genetic disorders of vision revealed by a behavioral screen of 400 essential loci in zebrafish

SCF Neuhauss, O Biehlmaier, MW Seeliger… - Journal of …, 1999 - Soc Neuroscience
We examined optokinetic and optomotor responses of 450 zebrafish mutants, which were
isolated previously based on defects in organ formation, tissue patterning, pigmentation, axon …

Guidelines for basic multifocal electroretinography (mfERG)

…, D Keating, M Kondo, MW Seeliger… - Documenta …, 2003 - search.proquest.com
Full-field electroretinography (ERG) is a standard clinical test for evaluating the function of
the retina as a whole [1]. Multifocal electroretinography (mfERG)" is a new technique that …

Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3

M Biel, M Seeliger, A Pfeifer, K Kohler… - Proceedings of the …, 1999 - National Acad Sciences
Two types of photoreceptors, rods and cones, coexist in the vertebrate retina. An in-depth
analysis of the retinal circuitry that transmits rod and cone signals has been hampered by the …

Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure

…, J Klooster, S Geiger, MW Seeliger… - Journal of cell …, 2004 - journals.biologists.com
Loss of Crumbs homologue 1 (CRB1) function causes either the eye disease Leber congenital
amaurosis or progressive retinitis pigmentosa, depending on the amount of residual …

Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice

…, HG Hartwig, A Huth, MW Seeliger… - The FASEB …, 2002 - Wiley Online Library
Taurine is involved in cell volume homeostasis, antioxidant defense, protein stabilization,
and stress responses. High levels of intracellular taurine are maintained by a Na + ‐dependent …

A portable albumin binder from a DNA‐encoded chemical library

…, M Drumea‐Mirancea, MW Seeliger… - Angewandte …, 2008 - Wiley Online Library
Albumin represents the most abundant protein in human plasma, at a concentration of 45
mgmLÀ1. To keep physiological production rates to a minimum, albumin displays a long …