User profiles for Mathieu Lafourcade

Mathieu Lafourcade

- Verified email at mit.edu - Cited by 2859

Mathieu Lafourcade

- Verified email at lirmm.fr - Cited by 1733

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

…, SSJ Hu, G Woodruff, S Fung, M Lafourcade… - Nature …, 2010 - nature.com
The endocannabinoid 2-arachidonoylglycerol (2-AG) regulates neurotransmission and
neuroinflammation by activating CB 1 cannabinoid receptors on neurons and CB 2 cannabinoid …

Transition to addiction is associated with a persistent impairment in synaptic plasticity

…, N Berson, E Balado, M Lafourcade… - Science, 2010 - science.org
Chronic exposure to drugs of abuse induces countless modifications in brain physiology.
However, the neurobiological adaptations specifically associated with the transition to …

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions

M Lafourcade, T Larrieu, S Mato, A Duffaud… - Nature …, 2011 - nature.com
The corollaries of the obesity epidemic that plagues developed societies are malnutrition and
resulting biochemical imbalances. Low levels of essential n-3 polyunsaturated fatty acids (n…

[HTML][HTML] Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex

M Lafourcade, I Elezgarai, S Mato, Y Bakiri, P Grandes… - PloS one, 2007 - journals.plos.org
Background Cannabinoids have deleterious effects on prefrontal cortex (PFC)-mediated
functions and multiple evidences link the endogenous cannabinoid (endocannabinoid) system, …

Reversing behavioural abnormalities in mice exposed to maternal inflammation

Y Shin Yim, A Park, J Berrios, M Lafourcade… - Nature, 2017 - nature.com
Viral infection during pregnancy is correlated with increased frequency of neurodevelopmental
disorders, and this is studied in mice prenatally subjected to maternal immune activation (…

Making people play for Lexical Acquisition with the JeuxDeMots prototype

M Lafourcade - SNLP'07: 7th international symposium on natural …, 2007 - hal.science
Lexical and semantic information are difficult to collect either automatically or manually, and
as being instrumental in many (if not all) NLP applications, there is a serious bottleneck for …

[PDF][PDF] Enhanced dendritic compartmentalization in human cortical neurons

…, EHS Toloza, MS Van der Goes, M Lafourcade… - Cell, 2018 - cell.com
The biophysical features of neurons shape information processing in the brain. Cortical
neurons are larger in humans than in other species, but it is unclear how their size affects …

Surface trafficking of neurotransmitter receptor: comparison between single-molecule/quantum dot strategies

L Groc, M Lafourcade, M Heine, M Renner… - Journal of …, 2007 - Soc Neuroscience
The cellular traffic of neurotransmitter receptors has captured a lot of attention over the last
decade, mostly because synaptic receptor number is adjusted during synaptic development …

Polymodal activation of the endocannabinoid system in the extended amygdala

N Puente, Y Cui, O Lassalle, M Lafourcade… - Nature …, 2011 - nature.com
The reason why neurons synthesize more than one endocannabinoid (eCB) and how this is
involved in the regulation of synaptic plasticity in a single neuron is not known. We found …

Metamodel matching for automatic model transformation generation

JR Falleri, M Huchard, M Lafourcade… - … Conference on Model …, 2008 - Springer
Applying Model-Driven Engineering (MDE) leads to the creation of a large number of
metamodels, since MDE recommends an intensive use of models defined by metamodels. …