During CNS development, oligodendrocytes wrap their plasma membrane around axons to
generate multilamellar myelin sheaths. To drive growth at the leading edge of myelin at the …

Methods of blind source separation are used in many contexts to separate composite data
sets according to their sources. Multiply labeled fluorescence microscopy images represent …

Neuron–glia interactions play a key role in maintaining and regulating the central nervous
system. Glial cells are implicated in the function of dopamine neurons and regulate their …

Pyramidal neurons of the neocortex can be subdivided into two major groups: deep- (DL)
and upper-layer (UL) neurons. Here we report that the expression of the AT-rich DNA-binding …

Age-associated decline in regeneration capacity limits the restoration of nervous system
functionality after injury. In a model for demyelination, we found that old mice fail to resolve the …

Nedd4-1 is a "neuronal precursor cell expressed and developmentally downregulated protein"
and among the most abundant E3 ubiquitin ligases in mammalian neurons. In analyses …

The community-driven initiative Quality Assessment and Reproducibility for Instruments &
Images in Light Microscopy (QUAREP-LiMi) wants to improve reproducibility for light …

Recombinant human erythropoietin (EPO) improves cognitive performance in neuropsychiatric
diseases ranging from schizophrenia and multiple sclerosis to major depression and …

l-3, 4-dihydroxyphenylalanine (l-DOPA) is the most effective treatment for Parkinson's disease
but can induce debilitating abnormal involuntary movements (dyskinesia). Here we show …

The ability of somatosensory neurons to perceive mechanical stimuli relies on specialized
mechanotransducing proteins and their molecular environment. Only recently has the identity …