User profiles for Michael Ambler

Michael ambler

University of Bristol
Verified email at bristol.ac.uk
Cited by 181

[HTML][HTML] Evidence for a causal link between sepsis and long-term mortality: a systematic review of epidemiologic studies

M Shankar-Hari, M Ambler, V Mahalingasivam… - Critical Care, 2016 - Springer
Background In addition to acute hospital mortality, sepsis is associated with higher risk of
death following hospital discharge. We assessed the strength of epidemiological evidence …

Neurons in the dorsomedial hypothalamus promote, prolong, and deepen torpor in the mouse

M Ambler, T Hitrec, A Wilson, M Cerri… - Journal of …, 2022 - Soc Neuroscience
Torpor is a naturally occurring, hypometabolic, hypothermic state engaged by a wide range
of animals in response to imbalance between the supply and demand for nutrients. Recent …

Solid–liquid interfacial free energy of ice Ih, ice Ic, and ice 0 within a mono-atomic model of water via the capillary wave method

M Ambler, B Vorselaars, MP Allen… - The Journal of Chemical …, 2017 - pubs.aip.org
We apply the capillary wave method, based on measurements of fluctuations in a ribbon-like
interfacial geometry, to determine the solid–liquid interfacial free energy for both polytypes …

Explainable hierarchical clustering for patient subtyping and risk prediction

…, A Hepburn, RS Bhamber, M Ambler… - Experimental …, 2023 - journals.sagepub.com
We present a pipeline in which machine learning techniques are used to automatically identify
and evaluate subtypes of hospital patients admitted between 2017 and 2021 in a large …

Protein recycling and limb muscle recovery after critical illness in slow-and fast-twitch limb muscle

S Preau, M Ambler, A Sigurta… - American Journal …, 2019 - journals.physiology.org
An impaired capacity of muscle to regenerate after critical illness results in long-term functional
disability. We previously described in a long-term rat peritonitis model that gastrocnemius …

[HTML][HTML] Turn it off and on again: characteristics and control of torpor

M Ambler, T Hitrec, A Pickering - Wellcome Open Research, 2021 - ncbi.nlm.nih.gov
Torpor is a hypothermic, hypoactive, hypometabolic state entered into by a wide range of
animals in response to environmental challenge. This review summarises the current …

Identification, explanation and clinical evaluation of hospital patient subtypes

E Werner, JN Clark, RS Bhamber, M Ambler… - … Workshop on Health …, 2023 - Springer
We present a pipeline in which unsupervised machine learning techniques are used to
automatically identify subtypes of hospital patients admitted between 2017 and 2021 in a large …

[HTML][HTML] The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated …

MT Ambler, LM Dubowitz, R Arunjerdja, EP Hla… - Malaria journal, 2009 - Springer
Background Mefloquine and artesunate combination therapy is the recommended first-line
treatment for uncomplicated malaria throughout much of south-east Asia. Concerns have …

Does Intermittent Nutrition Enterally Normalise hormonal and metabolic responses to feeding in critically ill adults? A protocol for the DINE-Normal proof-of-concept …

…, M Thomas, B Borislavova, HA Smith, M Ambler… - medRxiv, 2024 - medrxiv.org
Introduction: Over half of patients who spend >48 hours in the intensive care unit (ICU) are
fed via a nasogastric (NG) tube. Current guidance recommends continuous delivery of feed …

[BOOK][B] Agile modeling: effective practices for extreme programming and the unified process

S Ambler - 2002 - books.google.com
Ambler clearly explains AM, and shows readers how to incorporate AM, UML, and RUP into
their development projects with the help of numerous case studies integrated throughout the …