Molecular mediators of hypoxic–ischemic injury and implications for epilepsy in the developing brain
MA Hossain - Epilepsy & Behavior, 2005 - Elsevier
Perinatal hypoxia–ischemia (HI) is the most common cause of cerebral palsy, and an
important consequence of perinatal HI is epilepsy. Epilepsy is a disorder in which the balance …
important consequence of perinatal HI is epilepsy. Epilepsy is a disorder in which the balance …
Hypoxic-ischemic injury in neonatal brain: involvement of a novel neuronal molecule in neuronal cell death and potential target for neuroprotection
MA Hossain - International Journal of Developmental Neuroscience, 2008 - Elsevier
Perinatal hypoxia-ischemia (HI) is the most common cause of various neurological disabilities
in children with high societal cost. Hypoxic-ischemic brain damage is an evolving process …
in children with high societal cost. Hypoxic-ischemic brain damage is an evolving process …
Akt as a mediator of cell death
HR Luo, H Hattori, MA Hossain… - Proceedings of the …, 2003 - National Acad Sciences
Protein kinase B/Akt possesses prosurvival and antiapoptotic activities and is involved in
growth factor-mediated neuronal protection. In this study we establish Akt deactivation as a …
growth factor-mediated neuronal protection. In this study we establish Akt deactivation as a …
[HTML][HTML] Sex differences in mitochondrial biogenesis determine neuronal death and survival in response to oxygen glucose deprivation and reoxygenation
J Sharma, MV Johnston, MA Hossain - BMC neuroscience, 2014 - Springer
Background Mitochondrial dysfunction has been linked to neuronal death and a wide array
of neurodegenerative diseases. Previously, we have shown sex differences in mitochondria-…
of neurodegenerative diseases. Previously, we have shown sex differences in mitochondria-…
Quantitative cortical mapping of fractional anisotropy in developing rat brains
H Huang, A Yamamoto, MA Hossain… - Journal of …, 2008 - Soc Neuroscience
Cortical development is associated with a series of events that involve axon and dendrite
growth and synaptic formation. Although these developmental processes have been …
growth and synaptic formation. Although these developmental processes have been …
Neuroprotection by scatter factor/hepatocyte growth factor and FGF‐1 in cerebellar granule neurons is phosphatidylinositol 3‐kinase/akt‐dependent and MAPK/CREB …
MA Hossain, JC Russell, R Gomes… - Journal of …, 2002 - Wiley Online Library
Neuroprotective actions of scatter factor/hepatocyte growth factor (SF/HGF) have not been
described. We examined the effects of SF/HGF in comparison to acidic fibroblast growth factor‐…
described. We examined the effects of SF/HGF in comparison to acidic fibroblast growth factor‐…
Enhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxia
…, ME Blue, MV Johnston, S Naidu, MA Hossain - Neuroscience, 2007 - Elsevier
Rett syndrome (RTT) is associated with mutations in the transcriptional repressor gene
MeCP2. Although the clinical and neuropathological signs of RTT suggest disrupted synaptic …
MeCP2. Although the clinical and neuropathological signs of RTT suggest disrupted synaptic …
[HTML][HTML] Induction of vascular endothelial growth factor in human astrocytes by lead: involvement of a protein kinase C/activator protein-1 complex-dependent and …
MA Hossain, CML Bouton, J Pevsner… - Journal of Biological …, 2000 - ASBMB
The mechanism(s) underlying lead neurotoxicity are not fully elucidated. cDNA expression
microarray analysis identified lead-sensitive genes in immortalized human fetal astrocytes (SV…
microarray analysis identified lead-sensitive genes in immortalized human fetal astrocytes (SV…
Neuronal pentraxin 1: a novel mediator of hypoxic-ischemic injury in neonatal brain
MA Hossain, JC Russell, R O'Brien… - Journal of …, 2004 - Soc Neuroscience
Neonatal hypoxic-ischemic brain injury is a major cause of neurological disability and mortality.
Its therapy will likely require a greater understanding of the discrete neurotoxic molecular …
Its therapy will likely require a greater understanding of the discrete neurotoxic molecular …
Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease
…, KH Gylys, LG Apostolova, MJ LaDu, MA Hossain… - Neurobiology of …, 2018 - Elsevier
Synaptic neurodegeneration is thought to be an early event initiated by soluble β-amyloid (Aβ)
aggregates that closely correlates with cognitive decline in Alzheimer disease (AD). …
aggregates that closely correlates with cognitive decline in Alzheimer disease (AD). …