There are exciting new developments regarding the molecular mechanisms involved in the
influence of circulating proinflammatory molecules within cells of the blood‐brain barrier (BBB…

The recent characterization of human homologues of Toll may be the missing link for the
transduction events leading to NF‐κB activity and proinflammatory gene transcription during …

The recent cloning of a second estrogen receptor (ER) provided a new tool to investigate
and clarify how estrogens are capable of communicating with the brain and influence gene …

An imbalance between remyelinating and demyelinating rates underlies degenerative
processes in demyelinating diseases such as multiple sclerosis. An optimal therapeutic strategy …

When released into the bloodstream, proinflammatory cytokines have the ability to trigger the
transcription of different genes in cells of the blood–brain barrier (BBB), including members …

… Moisan, and N. Laflamme collaborated in the conception of the study and the supervision
of data collection. All authors participated in reviewing and drafting the article. …

The recent characterization of human homologs of Toll may be the missing link for the
transduction events leading to nuclear factor‐κB (NF‐κB) activity and proinflammatory gene …

Expression of the inhibitory factor κBα (IκBα) reflects the activity of nuclear factor κB(NF‐κB)
and is a powerful tool to investigate the regulation of the transcription factor within the CNS. …

… 100 women was drawn from each of the four groups (N = 416) to reach the final optimal
sample size of approximately 50 in each group (N = 199). Selected women were contacted by a …

In this study we investigated whether induction of toll‐like receptor 2 (TLR2) amplifies the
effect of a cell wall component derived from gram‐positive bacteria, namely peptidoglycan (…