… The authors review the state of the art management for patients with osteosarcoma in North
America and Europe including the use of limb-salvage procedures and reconstruction as …

Peripheral chemosensitivity is clinically assessed by measuring the ventilatory response,
changes of muscle sympathetic nerve activity, or physiological changes in heart rate or blood …

Curative therapy for childhood cancer has improved significantly in the last 2 decades such
that, at present, ∼80% of all children with cancer are likely to survive ≥5 years after …

Background Only a few small studies have assessed the long-term morbidity that follows the
treatment of childhood cancer. We determined the incidence and severity of chronic health …

… Marina N. Long-term survivors of childhood cancer: the medical consequences of cure. …
Marina N. Long-term survivors of childhood cancer: the medical consequences of cure. …

Astrocytes provide structural and metabolic support for neuronal networks, but direct
evidence demonstrating their active role in complex behaviors is limited. Central respiratory …

The Children’s Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood,
Adolescent, and Young Adult Cancers are risk-based, exposure-related clinical practice …

Abstract Treatment for Hodgkin’s disease (HD) is associated with a variety of thyroid abnormalities,
including hypothyroidism, hyperthyroidism, and thyroid neoplasms. Due to the small …

This manuscript describes the experience from registration until randomisation for a cohort
of 2260 patients with osteosarcoma who joined the EURAMOS-1 trial. This includes pre-…

Background We designed the EURAMOS-1 trial to investigate whether intensified postoperative
chemotherapy for patients whose tumour showed a poor response to preoperative …