Hypertension susceptibility in women increases at the transition to menopause, termed
perimenopause, a state characterized by erratic estrogen fluctuation and extended hormone …

There are significant neurogenic and inflammatory influences on blood pressure, yet the role
played by each of these processes in the development of hypertension is unclear. Tumor …

Although opioid addiction has risen dramatically, the role of gender in addiction has been
difficult to elucidate. We previously found sex-dependent differences in the hippocampal …

Prescription opioid abuse is a serious public health issue. Recently, we showed that female
and male Sprague–Dawley rats acquire conditioned place preference (CPP) to the mu …

Cocaine-associated memories are critical drivers of relapse in cocaine-dependent individuals
that can be evoked by exposure to cocaine or stress. Whether these environmental stimuli …

… PB for 24 h. Brain blocks were transferred into 30% sucrose in PB for an additional 24 h and
then … Prior to probe labeling, slides were baked at 60C in a circulating oven for 1 h to ensure …

Within the hypothalamic paraventricular nucleus (PVN), estrogen receptor (ER) β and other
gonadal hormone receptors play a role in central cardiovascular processes. However, the …

Corticotropin-releasing factor receptors (CRFR1) contribute to stress-induced adaptations in
hippocampal structure and function that can affect learning and memory processes. Our …

Following oxycodone conditioned place preference (CPP) in naïve female and male
Sprague Dawley rats, delta- and mu-opioid receptors (DORs and MORs) redistribute in …

Hypertension is a risk factor for neurodegenerative disorders involving inflammation and
inflammatory cytokine-producing brain cells (microglia and astrocytes) in the hippocampus and …