User profiles for Nikolaus R. McFarland
Nikolaus R. McFarlandUniversity of Florida College of Medicine, Fixel Institute for Neurological Diseases Verified email at neurology.ufl.edu Cited by 7369 |
Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum
Clinical manifestations in diseases affecting the dopamine system include deficits in emotional,
cognitive, and motor function. Although the parallel organization of specific corticostriatal …
cognitive, and motor function. Although the parallel organization of specific corticostriatal …
Thalamic relay nuclei of the basal ganglia form both reciprocal and nonreciprocal cortical connections, linking multiple frontal cortical areas
NR McFarland, SN Haber - Journal of Neuroscience, 2002 - Soc Neuroscience
Thalamic relay nuclei transmit basal ganglia output to the frontal cortex, forming the last link
in corticobasal ganglia circuitry. The thalamus regulates cortical activity through differential …
in corticobasal ganglia circuitry. The thalamus regulates cortical activity through differential …
Insular cortical projections to functional regions of the striatum correlate with cortical cytoarchitectonic organization in the primate
M Chikama, NR McFarland, DG Amaral… - Journal of …, 1997 - Soc Neuroscience
We examined the striatal projections from different cytoarchitectonic regions of the insular
cortex using anterograde and retrograde techniques. The shell and medial ventral striatum …
cortex using anterograde and retrograde techniques. The shell and medial ventral striatum …
Convergent inputs from thalamic motor nuclei and frontal cortical areas to the dorsal striatum in the primate
NR McFarland, SN Haber - Journal of Neuroscience, 2000 - Soc Neuroscience
Current models of basal ganglia circuitry primarily associate the ventral thalamic nuclei with
relaying basal ganglia output to the frontal cortex. However, some studies have …
relaying basal ganglia output to the frontal cortex. However, some studies have …
The concept of the ventral striatum in nonhuman primates
SN Haber, NR McFARLAND - … of the New York Academy of …, 1999 - Wiley Online Library
The concept of the ventral striatum was first put forth by Heimer and Wilson to describe the
extension of basal ganglia elements into the olfactory tubercle. The ventral striatum includes …
extension of basal ganglia elements into the olfactory tubercle. The ventral striatum includes …
Free-water imaging in Parkinson's disease and atypical parkinsonism
Conventional single tensor diffusion analysis models have provided mixed findings in the
substantia nigra of Parkinson’s disease, but recent work using a bi-tensor analysis model has …
substantia nigra of Parkinson’s disease, but recent work using a bi-tensor analysis model has …
The place of the thalamus in frontal cortical-basal ganglia circuits
S Haber, NR Mcfarland - The Neuroscientist, 2001 - journals.sagepub.com
The thalamus has long been thought to convey subcortical information to the cortex. Indeed,
models of basal ganglia function attribute the primary role for the thalamus to a simple relay …
models of basal ganglia function attribute the primary role for the thalamus to a simple relay …
Progression marker of Parkinson's disease: a 4-year multi-site imaging study
Progression markers of Parkinson’s disease are crucial for successful therapeutic development.
Recently, a diffusion magnetic resonance imaging analysis technique using a bitensor …
Recently, a diffusion magnetic resonance imaging analysis technique using a bitensor …
Diagnostic approach to atypical parkinsonian syndromes
NR McFarland - Continuum: Lifelong Learning in Neurology, 2016 - journals.lww.com
Purpose of Review: Although increasingly recognized, atypical parkinsonian syndromes
remain challenging to diagnose and are underrecognized due to overlap with other …
remain challenging to diagnose and are underrecognized due to overlap with other …
α-Synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of parkinson disease
NR McFarland, Z Fan, K Xu… - … of Neuropathology & …, 2009 - academic.oup.com
Lewy bodies are found in Parkinson disease and related disorders and are extensively
phosphorylated at Ser-129 (S129), but whether S129 phosphorylation mediates α-synuclein …
phosphorylated at Ser-129 (S129), but whether S129 phosphorylation mediates α-synuclein …