User profiles for Nilima Prakash
Nilima PrakashProfessor of Applied Genetics and Stem Cell Biology, Hamm-Lippstadt University of Applied … Verified email at hshl.de Cited by 3010 |
Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP
…, D Acampora, R Prosperi, D Omodei, N Prakash… - Nature …, 2010 - nature.com
Mesencephalic-diencephalic dopaminergic neurons control locomotor activity and emotion
and are affected in neurodegenerative and psychiatric diseases. The homeoprotein Otx2 is …
and are affected in neurodegenerative and psychiatric diseases. The homeoprotein Otx2 is …
Genetic networks controlling the development of midbrain dopaminergic neurons
Recent data have substantially advanced our understanding of midbrain dopaminergic neuron
development. Firstly, a Wnt1‐regulated genetic network, including Otx2 and Nkx2‐2, and …
development. Firstly, a Wnt1‐regulated genetic network, including Otx2 and Nkx2‐2, and …
BMP/SMAD pathway promotes neurogenesis of midbrain dopaminergic neurons in vivo and in human induced pluripotent and neural stem cells
The embryonic formation of midbrain dopaminergic (mDA) neurons in vivo provides critical
guidelines for the in vitro differentiation of mDA neurons from stem cells, which are currently …
guidelines for the in vitro differentiation of mDA neurons from stem cells, which are currently …
[HTML][HTML] Bilateral maxillary brown tumors in a patient with primary hyperparathyroidism: Report of a rare entity and review of literature
N Soundarya, P Sharada, N Prakash… - Journal of Oral and …, 2011 - journals.lww.com
Brown tumors are erosive bony lesions caused by rapid osteoclastic activity and peritrabecular
fibrosis due to hyperparathyroidism, resulting in a local destructive phenomenon. The …
fibrosis due to hyperparathyroidism, resulting in a local destructive phenomenon. The …
A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo
Midbrain neurons synthesizing the neurotransmitter dopamine play a central role in the
modulation of different brain functions and are associated with major neurological and …
modulation of different brain functions and are associated with major neurological and …
Histological assessment of cellular changes in gingival epithelium in ante-mortem and post-mortem specimens
G Pradeep, K Uma, P Sharada, N Prakash - Journal of Forensic Dental …, 2009 - jfds.org
Background: Death is an irreversible cessation of circulation, respiration and cerebral
function. A number of continuous changes occur in the period after death, and these vary …
function. A number of continuous changes occur in the period after death, and these vary …
[HTML][HTML] Estimation of salivary sialic acid in oral premalignancy and oral squamous cell carcinoma
V Chaudhari, GL Pradeep, N Prakash… - Contemporary clinical …, 2016 - journals.lww.com
Aims: Oral cancer is the most life-threatening disease of oral tissues. In societies where the
incidence of oral cancer is high, clinically recognizable premalignant lesions are particularly …
incidence of oral cancer is high, clinically recognizable premalignant lesions are particularly …
A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation
MicroRNAs have emerged as key posttranscriptional regulators of gene expression during
vertebrate development. We show that the miR-200 family plays a crucial role for the proper …
vertebrate development. We show that the miR-200 family plays a crucial role for the proper …
Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons
…, G Masserdotti, N Prakash… - EMBO molecular …, 2022 - embopress.org
Direct reprogramming based on genetic factors resembles a promising strategy to replace
lost cells in degenerative diseases such as Parkinson's disease. For this, we developed a …
lost cells in degenerative diseases such as Parkinson's disease. For this, we developed a …
Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons
Pitx3 is a critical homeodomain transcription factor for the proper development and survival
of mesodiencephalic dopaminergic (mdDA) neurons in mammals. Several variants of this …
of mesodiencephalic dopaminergic (mdDA) neurons in mammals. Several variants of this …