User profiles for P. Krieg

Paul A Krieg

Professor of Molecular Biology, University of Arizona
Verified email at email.arizona.edu
Cited by 23126

What are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis?

G Fürstenberger, P Krieg… - … journal of cancer, 2006 - Wiley Online Library
Substantial evidence supports a functional role for cyclooxygenase‐ and lipoxygenase‐catalyzed
arachidonic and linoleic acid metabolism in cancer development. Genetic intervention …

The role of lipoxygenases in epidermis

P Krieg, G Fürstenberger - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
… LOX mutations account for 67% of these cases, with a specific ALOX12B mutation (p.Tyr521Cy…
In ALOXE3 two recurrent mutations (p.Arg234X found in 13 and p.Pro630Leu found in 15 …

[HTML][HTML] Notochord patterning of the endoderm

O Cleaver, PA Krieg - Developmental biology, 2001 - Elsevier
Endodermally derived organs of the gastrointestinal and respiratory system form at distinct
anterioposterior and dorsoventral locations along the vertebrate body axis. This stereotyped …

Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

DA Melton, PA Krieg, MR Rebagliati… - Nucleic acids …, 1984 - academic.oup.com
… The nucleotide at which SP6 RNA polymerase initiates transcription was identified by
labelling RNA transcripts with 32P-p-GTP and 32P-p-ATP. Only the 32P-p-GTP was incorporated …

[HTML][HTML] Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

…, L Sutherland, JA Richardson, E Small, PA Krieg… - Cell, 2001 - cell.com
… (A) Gel mobility shift assays were performed with a 32 P-labeled oligonucleotide probe for
SM22 CArG-near and in vitro translation products of FLAG-tagged myocardin in the presence …

Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs

PA Krieg, DA Melton - Nucleic Acids Research, 1984 - academic.oup.com
We describe a method for the synthesis of microgram quantities of eucaryotic messenger
RNAs. Injection into the cytoplasm of frog oocytes and addition to wheat germ extracts show …

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

…, Y Xing, JL Lubischer, PA Krieg… - Journal of …, 2008 - Soc Neuroscience
Understanding the cell–cell interactions that control CNS development and function has long
been limited by the lack of methods to cleanly separate neural cell types. Here we describe …

[25] In vitro RNA synthesis with SP6 RNA polymerase

PA Krieg, DA Melton - Methods in enzymology, 1987 - Elsevier
Publisher Summary This chapter discusses the in vitro ribonucleic acid (RNA) synthesis with
SP6 RNA polymerase. The chapter describes the use of in vitro transcription systems for the …

[HTML][HTML] Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors

…, A Visel, SM Xu, LA Pennacchio, I Dubchak, PA Krieg… - Cell, 2008 - cell.com
Vascular development begins when mesodermal cells differentiate into endothelial cells,
which then form primitive vessels. It has been hypothesized that endothelial-specific gene …

[HTML][HTML] Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog …

…, SL D'Agostino, MK Miller, RL Heimark, PA Krieg - Developmental …, 2006 - Elsevier
The peptide growth factor apelin is the high affinity ligand for the G-protein-coupled receptor
APJ. During embryonic development of mouse and frog, APJ receptor is expressed at high …