Extracellular single-cell recording and microiontophoretic techniques were used to characterize
the effects of cocaine on the activity of mesoaccumbens A10 dopamine (DA) neurons in …

Thirty children (age 10–16 years) suffering from unilateral hearing loss (UHL) were matched
with a control group and examined by a battery of psychological tests (verbal and non-…

A group of children suffering from unilateral hearing loss (UHL) were evaluated. Serological
tests were performed and vaccination against mumps was offered if negative. In 43.6% of …

Background The identification and treatment of psychiatric disorders in individuals with
autism spectrum disorders (ASD) and ID presents many challenges. We describe the …

The catalytic subunit of protein kinase A increases brain tryptophan hydroxylase activity.
The activation is manifested as an increase in V max without alterations in the K m for either …

Before the discovery of the metabotropic glutamate receptors (mGIuRs), the glutamate
analogue L-2-amino-4-phosphonobutanoic acid (L-AP4) was identified as a potent presynaptic …

The effect of protein kinase A on the catalytic activity and phosphorylation of brain tryptophan
hydroxylase was examined. Stimulation of endogenous protein kinase A by cyclic AMP or …

The electrophysiological effects of three selective D 1 dopamine (DA) receptor agonists,
which exhibit different potencies and efficacies for stimulation of adenylate cyclase, were …

Tryptophan hydroxylase (l-tryptophan, tetrahydropteridine: oxygen oxidoreductase [5-hydroxylating];
EC 1.14.16.4; TPH), the initial and rate-limiting enzyme in the biosynthesis of the …

The dopamine(DA) hypothesis of schizophrenia proposes hyperactivity of the mesocorticolimbic
DA system, originating within the Al 0 DA cells of the ventral tegmental area (VTA), as a …