User profiles for PW Reeh

Peter Reeh

em. Professor, Senior Fellow of Physiology, University of Erlangen
Verified email at fau.de
Cited by 20090

Sensory and signaling mechanisms of bradykinin, eicosanoids, platelet-activating factor, and nitric oxide in peripheral nociceptors

G Pethő, PW Reeh - Physiological reviews, 2012 - journals.physiology.org
Peripheral mediators can contribute to the development and maintenance of inflammatory
and neuropathic pain and its concomitants (hyperalgesia and allodynia) via two mechanisms. …

Tissue acidosis in nociception and pain

PW Reeh, KH Steen - Progress in brain research, 1996 - Elsevier
… and Reeh, PW (1996b) Inhibition of a capsaicin induced ionic current - a new mechanism
of action for asprin-like drugs ? mugen Arch., 431: R61. Krishtal, OA and Pidoplichko, VI (1980) …

Molecular physiology of proton transduction in nociceptors

PW Reeh, M Kress - Current Opinion in Pharmacology, 2001 - Elsevier
Recent cloning efforts have identified families of ion channels that may be involved in signaling
noxious proton accumulation in tissue. Some conduct potassium ions outward and are …

Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro

KH Steen, PW Reeh, F Anton… - Journal of …, 1992 - Soc Neuroscience
In ischemic and in inflamed tissues, pH levels down to 5.4 have been measured, and this
local acidosis may contribute to pain and hyperalgesia in disease states. To evaluate the role …

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

…, ME Cooper, U Haberkorn, M Brownlee, PW Reeh… - Nature medicine, 2012 - nature.com
This study establishes a mechanism for metabolic hyperalgesia based on the glycolytic
metabolite methylglyoxal. We found that concentrations of plasma methylglyoxal above 600 nM …

Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures

…, RW Carr, J Kobayashi, C Nau, JN Wood, PW Reeh - Nature, 2007 - nature.com
Sensory acuity and motor dexterity deteriorate when human limbs cool down, but pain
perception persists and cold-induced pain can become excruciating 1 . Evolutionary pressure to …

A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro

KH Steen, AE Steen, PW Reeh - Journal of Neuroscience, 1995 - Soc Neuroscience
… and Reeh, 1991). High hydrogen ion concentrations … Reeh PW (1986) Sensory receptors
in mammalian skin in an in … Steen KH, Reeh PW (1993) Sustained graded pain and …

Pain due to tissue acidosis: a mechanism for inflammatory and ischemic myalgia?

U Issberner, PW Reeh, KH Steen - Neuroscience letters, 1996 - Elsevier
… [15] Steen, KH and Reeh, PW, Sustained graded pain and hyperalgesia from harmless …
and Reeh, PW, Pain due to experimental acidosis in human skin: evidence for non-adapting …

Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro

M Kress, M Koltzenburg, PW Reeh… - Journal of …, 1992 - journals.physiology.org
1. The purpose of the present study was to compare the responsiveness unmyelinated
cutaneous units in vivo and in vitro and to determine the proportion of primary afferents …

Sensory receptors in mammalian skin in an in vitro preparation

PW Reeh - Neuroscience letters, 1986 - Elsevier
… These quantitative data will be published at a later date (Reeh, Cop, Szolcs/myi and Handwerker:
… and Reeh, PW, Discharge patterns of afferent cutaneous nerve fibres from the rat's tail …