Tumor necrosis factor-alpha is produced by dying retinal neurons and is required for Müller glia proliferation during zebrafish retinal regeneration

CM Nelson, KM Ackerman, P O'Hayer… - Journal of …, 2013 - Soc Neuroscience
Intense light exposure causes photoreceptor apoptosis in dark-adapted adult albino zebrafish
(Danio rerio). Subsequently, Müller glia increase expression of the Achaete-scute complex…

In-hospital cardiac arrest in critically ill patients with covid-19: multicenter cohort study

…, H Berlin, M Pan, C Meloche, R Feroz, P O'Hayer… - bmj, 2020 - bmj.com
Objectives To estimate the incidence, risk factors, and outcomes associated with in-hospital
cardiac arrest and cardiopulmonary resuscitation in critically ill adults with coronavirus …

[HTML][HTML] Soluble urokinase receptor (SuPAR) in COVID-19–related AKI

…, HR Shadid, P Blakely, P O'Hayer… - Journal of the …, 2020 - journals.lww.com
Background AKI commonly occurs in patients with coronavirus disease 2019 (COVID-19). Its
pathogenesis is poorly understood. The urokinase receptor system is a key regulator of the …

Inflammation, hyperglycemia, and adverse outcomes in individuals with diabetes mellitus hospitalized for COVID-19

…, I Khaleel, K Padalia, C Meloche, P O'hayer… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE Diabetes mellitus (DM) is a major risk factor for severe coronavirus disease
2019 (COVID-19) for reasons that are unclear. RESEARCH DESIGN AND METHODS We …

EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells

…, YC Chen, N Deng, A Pearson, YS Niknafs, P O'Hayer… - Cancer research, 2016 - AACR
Little is known about the factors that regulate the asymmetric division of cancer stem–like
cells (CSC). Here, we demonstrate that EGFL6, a stem cell regulatory factor expressed in …

Relationship between preexisting cardiovascular disease and death and cardiovascular outcomes in critically ill patients with COVID-19

…, H Shadid, H Berlin, M Pan, P O'Hayer… - … quality and outcomes, 2022 - Am Heart Assoc
Background: Preexisting cardiovascular disease (CVD) is perceived as a risk factor for poor
outcomes in patients with COVID-19. We sought to determine whether CVD is associated …

[HTML][HTML] CDK4/6 inhibition as maintenance and combination therapy for high grade serous ovarian cancer

M Iyengar, P O'Hayer, A Cole, T Sebastian, K Yang… - Oncotarget, 2018 - ncbi.nlm.nih.gov
High grade serous ovarian cancer (HGSOC) is a disease with a high relapse rate and poor
overall survival despite good initial responses to platinum-based therapy. Cell cycle …

Angiotensin‐converting enzyme inhibitors, angiotensin II receptor blockers, and outcomes in patients hospitalized for COVID‐19

…, H Berlin, K Padalia, P O'hayer… - Journal of the …, 2021 - Am Heart Assoc
Background Use of angiotensin‐converting enzyme inhibitors and angiotensin receptor
blockers (ACEi/ARB) is thought to affect COVID‐19 through modulating levels of angiotensin‐…

[HTML][HTML] NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer

AJ Cole, M Iyengar, S Panesso-Gómez, P O'Hayer… - JCI insight, 2020 - ncbi.nlm.nih.gov
Abstract Development of chemotherapy resistance is a major problem in ovarian cancer. One
understudied mechanism of chemoresistance is the induction of quiescence, a reversible …

Differences in inflammation, treatment, and outcomes between black and non-black patients hospitalized for COVID-19: a prospective cohort study

…, M Pan, HR Shadid, K Padalia, P O'Hayer… - The American Journal of …, 2022 - Elsevier
Purpose Racial disparities in coronavirus disease 2019 (COVID-19) outcomes have been
described. We sought to determine whether differences in inflammatory markers, use of COVID…