Parkinson's disease (PD) is one of the most common neurodegenerative disorders. Several
toxin-induced animals models simulate the motor deficits occurring in PD. Among them, the …

High fat diets and obesity pose serious health problems, such as type II diabetes and
cardiovascular disease. Impaired cognitive function is also associated with high fat intake. In this …

Hippocampus-mediated learning enhances neurogenesis in the adult dentate gyrus (DG),
and this process has been suggested to be involved in memory formation. The hippocampus …

… Helena Frielingsdorf, Katherine Schwarz, Patrik Brundin, and Paul Mohapel… Paul Mohapel * …

We investigated whether cell proliferation and neurogenesis are altered in R6/2 transgenic
Huntington's disease mice. Using bromodeoxyuridine (BrdU), we found a progressive …

Major depression is often associated with elevated glucocorticoid levels. High levels of
glucocorticoids reduce neurogenesis in the adult rat hippocampus. Electroconvulsive seizures (…

Evidence has accumulated that apoptotic cell death contributes to brain damage following
experimental seizures. A substantial number of degenerating neurons within limbic regions …

The effects of icv infused platelet-derived growth factor and brain-derived neurotrophic factor
on cell genesis, as assessed with bromodeoxyuridine (BrdU) incorporation, were studied in …

3,4-Dihydroxyphenyl-l-alanine (l-DOPA)-induced dyskinesia is associated with molecular and
synaptic plasticity in the basal ganglia, but the occurrence of structural remodeling through …

Status epilepticus (SE) is characterized by continual seizure activity that can vary widely in
the intensity of convulsions. We induced seizures by applying continuous electrical …