An important role for the neural extracellular matrix in modulating cortical activity-dependent
synaptic plasticity has been established by a number of recent studies. However, …

Although environmental enrichment improves spatial memory and alters synaptic plasticity
in aged rodents, it is unclear whether all types of enrichment treatments yield similar benefits. …

During development the extracellular matrix (ECM) of the central nervous system (CNS)
facilitates proliferation, migration, and synaptogenesis. In the mature nervous system due to …

Objective We previously reported loss of perineuronal net ( PN ) immunohistochemical staining
around parvalbumin‐positive interneurons in the hippocampus of rats after an episode of …

In the rodent model of temporal lobe epilepsy, there is extensive synaptic reorganization
within the hippocampus following a single prolonged seizure event, after which animals …

Increased neuronal plasticity and neuronal cell loss has been implicated in the development
of epilepsy following injury. Parvalbumin fast spiking inhibitory interneurons have a robust …

The perineuronal net (PN), a component of the neural extracellular matrix (ECM), is a dynamic
structure whose expression decreases following diminished physiological activity. Here, …

Autism symptoms, including impairments in language development, social interactions, and
motor skills, have been difficult to model in rodents. Since children exposed in utero to …

Stress-related illnesses like Major Depressive Disorder (MDD) are at least twice as prevalent
in women as in men, but it is not known whether this phenomenon has a neurobiological …

… To Paulette McRae for sharing the joys and dreams of sisterhood, conversing and laughing
with no inhibition, inspiring me constantly to become a better person, and so much more ... …