User profiles for Peter Serrano

Peter Serrano

Professor of Psychology, Hunter College
Verified email at genectr.hunter.cuny.edu
Cited by 5139

Storage of spatial information by the maintenance mechanism of LTP

E Pastalkova, P Serrano, D Pinkhasova, E Wallace… - science, 2006 - science.org
Analogous to learning and memory storage, long-term potentiation (LTP) is divided into
induction and maintenance phases. Testing the hypothesis that the mechanism of LTP …

Protein kinase Mζ is necessary and sufficient for LTP maintenance

DSF Ling, LS Benardo, PA Serrano, N Blace… - Nature …, 2002 - nature.com
Long-term potentiation (LTP), a persistent synaptic enhancement thought to be a substrate
for memory 1 , can be divided into two phases: induction, triggering potentiation, and …

PKMζ maintains late long-term potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors

Y Yao, MT Kelly, S Sajikumar, P Serrano… - Journal of …, 2008 - Soc Neuroscience
Although the maintenance mechanism of late long-term potentiation (LTP) is critical for the
storage of long-term memory, the expression mechanism of synaptic enhancement during late…

[HTML][HTML] Protein kinase Mζ synthesis from a brain mRNA encoding an independent protein kinase Cζ catalytic domain: implications for the molecular mechanism of …

AI Hernandez, N Blace, JF Crary, PA Serrano… - Journal of Biological …, 2003 - ASBMB
Protein kinase Mζ (PKMζ) is a newly described form of PKC that is necessary and sufficient
for the maintenance of hippocampal long term potentiation (LTP) and the persistence of …

[HTML][HTML] PKMζ maintains spatial, instrumental, and classically conditioned long-term memories

P Serrano, EL Friedman, J Kenney, SM Taubenfeld… - PLoS …, 2008 - journals.plos.org
How long-term memories are stored is a fundamental question in neuroscience. The first
molecular mechanism for long-term memory storage in the brain was recently identified as the …

Persistent phosphorylation by protein kinase Mζ maintains late-phase long-term potentiation

P Serrano, Y Yao, TC Sacktor - Journal of Neuroscience, 2005 - Soc Neuroscience
Protein kinase Mζ (PKMζ), an autonomously active atypical PKC isoform, is both necessary
and sufficient for enhanced synaptic transmission during long-term potentiation (LTP) …

Enhanced learning after genetic overexpression of a brain growth protein

…, I Cantallops, S Zaffuto, P Serrano… - Proceedings of the …, 2000 - National Acad Sciences
Ramón y Cajal proposed 100 years ago that memory formation requires the growth of nerve
cell processes. One-half century later, Hebb suggested that growth of presynaptic axons …

Vicarious social defeat stress induces depression-related outcomes in female mice

…, MA Hernandez, DO Sanchez, MK Lobo, PA Serrano… - Biological …, 2018 - Elsevier
Background Stress is a prevailing risk factor for mood-related illnesses, wherein women
represent the majority of those affected by major depression. Despite the growing literature …

Short-term, intermediate-term, and long-term memories

…, EL Bennett, PJ Colombo, DW Lee, PA Serrano - Behavioural brain …, 1993 - Elsevier
This paper focuses on the temporal dimension of memory formation and storage. Is the
usual two-fold separation between short-term memory (STM) and long-term memory (LTM) …

[PDF][PDF] Distinct NMDA receptor subpopulations contribute to long-term potentiation and long-term depression induction

S Hrabetova, P Serrano, N Blace… - The Journal of …, 2000 - Soc Neuroscience
Long-term potentiation (LTP) and long-term depression (LTD) are persistent modifications of
synaptic strength that have been implicated in learning, memory, and neuronal development…