Nonrandom local circuits in the dentate gyrus

P Larimer, BW Strowbridge - Journal of Neuroscience, 2008 - Soc Neuroscience
The dentate hilus has been extensively studied in relation to its potential role in memory and
in temporal lobe epilepsy. Little is known, however, about the synapses formed between the …

Semilunar granule cells: glutamatergic neurons in the rat dentate gyrus with axon collaterals in the inner molecular layer

PA Williams, P Larimer, Y Gao… - Journal of …, 2007 - Soc Neuroscience
Synaptic reorganization of the dentate gyrus inner molecular layer (IML) is a pathophysiological
process that may facilitate seizures in patients with temporal-lobe epilepsy. Two …

Representing information in cell assemblies: persistent activity mediated by semilunar granule cells

P Larimer, BW Strowbridge - Nature neuroscience, 2010 - nature.com
Here we found that perforant path stimulation in rat hippocampal slices evoked long-lasting
barrages of synaptic inputs in subpopulations of dentate gyrus mossy cells and hilar …

Phasic stimuli evoke precisely timed spikes in intermittently discharging mitral cells

R Balu, P Larimer… - Journal of …, 2004 - journals.physiology.org
Mitral cells, the principal cells of the olfactory bulb, respond to sensory stimulation with precisely
timed patterns of action potentials. By contrast, the same neurons generate intermittent …

Secretagogin is expressed by developing neocortical GABAergic neurons in humans but not mice and increases neurite arbor size and complexity

CS Raju, J Spatazza, A Stanco, P Larimer… - Cerebral …, 2018 - academic.oup.com
The neocortex of primates, including humans, contains more abundant and diverse inhibitory
neurons compared with rodents, but the molecular foundations of these observations are …

Amplitude modulation coding in awake mice and squirrel monkeys

NEG Hoglen, P Larimer, EAK Phillips… - Journal of …, 2018 - journals.physiology.org
Both mice and primates are used to model the human auditory system. The primate order
possesses unique cortical specializations that govern auditory processing. Given the power of …

[PDF][PDF] Caudal ganglionic eminence precursor transplants disperse and integrate as lineage-specific interneurons but do not induce cortical plasticity

P Larimer, J Spatazza, JS Espinosa, Y Tang, M Kaneko… - Cell reports, 2016 - cell.com
The maturation of inhibitory GABAergic cortical circuits regulates experience-dependent
plasticity. We recently showed that the heterochronic transplantation of parvalbumin (PV) or …

Number of patient-reported allergies helps distinguish epilepsy from psychogenic nonepileptic seizures

NM Robbins, P Larimer, JA Bourgeois… - Epilepsy & Behavior, 2016 - Elsevier
Psychogenic nonepileptic seizures (PNES) are relatively common, accounting for 5–40% of
visits to tertiary epilepsy centers. Inpatient video-electroencephalogram (vEEG) monitoring is …

Development and long-term integration of MGE-lineage cortical interneurons in the heterochronic environment

P Larimer, J Spatazza, MP Stryker… - Journal of …, 2017 - journals.physiology.org
Interneuron precursors transplanted into visual cortex induce network plasticity during their
heterochronic maturation. Such plasticity can have a significant impact on the function of the …

Timing is everything

P Larimer, BW Strowbridge - Nature, 2007 - nature.com
Phillip LarimerPhillip Larimer and Ben W. Strowbridge are in the Department of
Neurosciences, Case Western Reserve University, Cleveland, Ohio 44106, USA. bens@case.edu …